Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 13/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 12/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 12/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 12/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 12/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 12/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 12/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 12/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | ICMT | O60725 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10467960 | 1.00 | GPR84 (0.44) | GPR84HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL10466595 | 1.00 | GPR84 (0.44) | GPR84HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL10466056 | 1.00 | GPR84 (0.44) | GPR84HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL10570632 | 1.00 | GPR84 (0.44) | GPR84HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL10467234 | 0.99 | GPR84 (0.46) | GPR84HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL10467635 | 0.99 | GPR84 (0.46) | GPR84HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL10467632 | 0.99 | GPR84 (0.46) | GPR84HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL10469080 | 0.95 | GPR84 (0.47) | GPR84HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL10468796 | 0.90 | HDAC3 (0.51) | GPR84HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL10468191 | 0.87 | GPR84 (0.57) | GPR84SLC6A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4940709-A | PLATELET ACTIVATING FACTOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-07-10 | — | — | US | disclosed |
| EP-0181152-B1 | PIPERAZINE COMPOUND AS PAF-ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-13 | — | — | EP | disclosed |
| US-4806538-A | ANTICOAGULANT, HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-02-21 | — | — | US | disclosed |
| EP-0181152-A1 | Piperazine compound as PAF-antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-14 | — | — | EP | disclosed |