Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | FOS | P01100 | 1/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10468073 | 1.00 | MEN1 (0.51) | MEN1KMT2APOLBSMN1; SMN2CRHBP | |
| SCHEMBL10469701 | 1.00 | MEN1 (0.51) | MEN1KMT2APOLBSMN1; SMN2CRHBP | |
| SCHEMBL10468074 | 1.00 | MEN1 (0.51) | MEN1KMT2APOLBSMN1; SMN2CRHBP | |
| SCHEMBL10467463 | 0.80 | KDM1A (0.53) | MEN1KMT2APOLBSMN1; SMN2CRHBP | |
| SCHEMBL10467987 | 0.80 | LMNA (0.41) | MEN1KMT2APOLBGRIN2BALDH1A1 | |
| SCHEMBL10467989 | 0.80 | LMNA (0.41) | MEN1KMT2APOLBGRIN2BALDH1A1 | |
| SCHEMBL10467452 | 0.80 | LMNA (0.41) | MEN1KMT2APOLBGRIN2BALDH1A1 | |
| SCHEMBL10467453 | 0.80 | LMNA (0.41) | MEN1KMT2APOLBGRIN2BALDH1A1 | |
| SCHEMBL10467674 | 0.80 | LMNA (0.41) | MEN1KMT2APOLBGRIN2BALDH1A1 | |
| SCHEMBL10467434 | 0.80 | LMNA (0.41) | MEN1KMT2APOLBGRIN2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4927826-A | Cycloproylpropenamides useful as platelet activing factor (PAF) antagonists | HOFFMAN-LA ROCHE INC. (US) | 1990-05-22 | — | — | US | disclosed |
| US-4786646-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | HOFFMANN-LA ROCHE INC. (US) | 1988-11-22 | — | — | US | disclosed |