Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 4/20 | 0.45 |
| ▸ | CTSS | P25774 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KYNU | Q16719 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 4/20 | 0.44 |
| ▸ | CTSB | P07858 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10772587 | 0.93 | KDM4E (0.48) | CTSLCTSSKDM4EMEN1KMT2A | |
| SCHEMBL10467554 | 0.93 | KDM4E (0.48) | CTSLCTSSKDM4EMEN1KMT2A | |
| SCHEMBL10466993 | 0.88 | TRPM8 (0.43) | TRPM8CTSLCTSSALDH1A1ALOX15 | |
| SCHEMBL10466059 | 0.87 | TRPM8 (0.45) | TRPM8CTSLCTSSALDH1A1ALOX15 | |
| Methoxymethane SCHEMBL10772620 | 0.82 | CYP3A4 (0.43) | CTSLCTSSMEN1KMT2ALMNA | |
| Methoxymethane SCHEMBL10468364 | 0.82 | CYP3A4 (0.43) | CTSLCTSSMEN1KMT2ALMNA | |
| Methoxymethane SCHEMBL10467400 | 0.81 | KDM4E (0.50) | CTSLCTSSALDH1A1KDM4EMEN1 | |
| Methoxymethane SCHEMBL10775780 | 0.81 | KDM4E (0.50) | CTSLCTSSALDH1A1KDM4EMEN1 | |
| SCHEMBL10467546 | 0.81 | TRPM8 (0.45) | TRPM8CTSLCTSSALDH1A1ALOX15 | |
| SCHEMBL10776104 | 0.80 | TRPM8 (0.47) | TRPM8CTSLCTSSALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4940709-A | PLATELET ACTIVATING FACTOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-07-10 | — | — | US | disclosed |
| EP-0181152-B1 | PIPERAZINE COMPOUND AS PAF-ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-13 | — | — | EP | disclosed |
| US-4806538-A | ANTICOAGULANT, HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-02-21 | — | — | US | disclosed |