Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 5/20 | 0.42 |
| ▸ | CTSS | P25774 | 5/20 | 0.42 |
| ▸ | CTSB | P07858 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 6/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methoxymethane SCHEMBL10775780 | 1.00 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10CYP3A4CYP2D6 | |
| SCHEMBL10772587 | 0.86 | KDM4E (0.48) | KDM4ECYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10467554 | 0.86 | KDM4E (0.48) | KDM4ECYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10465913 | 0.83 | MEN1 (0.42) | ALDH1A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10466059 | 0.82 | TRPM8 (0.45) | ALDH1A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10469072 | 0.81 | TRPM8 (0.47) | KDM4EALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL10466223 | 0.80 | MEN1 (0.45) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL10467639 | 0.80 | CTSL (0.44) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL10775734 | 0.80 | MEN1 (0.45) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL10778892 | 0.80 | CTSL (0.44) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4940709-A | PLATELET ACTIVATING FACTOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-07-10 | — | — | US | disclosed |
| US-4806538-A | ANTICOAGULANT, HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-02-21 | — | — | US | disclosed |