Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 5/20 | 0.45 |
| ▸ | ANPEP | P15144 | 2/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10470158 | 0.84 | ATM (0.47) | MEN1KMT2AALDH1A1PIK3CDGAA | |
| SCHEMBL2059306 | 0.81 | KMT2A (0.60) | MEN1KMT2AALDH1A1MMP2ANPEP | |
| SCHEMBL27745576 | 0.81 | KMT2A (0.60) | MEN1KMT2AALDH1A1MMP2ANPEP | |
| SCHEMBL6196385 | 0.81 | KMT2A (0.60) | MEN1KMT2AALDH1A1MMP2ANPEP | |
| SCHEMBL10390327 | 0.81 | KMT2A (0.60) | MEN1KMT2AALDH1A1MMP2ANPEP | |
| SCHEMBL13326445 | 0.81 | KMT2A (0.60) | MEN1KMT2AALDH1A1MMP2ANPEP | |
| SCHEMBL6196388 | 0.81 | KMT2A (0.60) | MEN1KMT2AALDH1A1MMP2ANPEP | |
| SCHEMBL8132886 | 0.81 | KMT2A (0.60) | MEN1KMT2AALDH1A1MMP2ANPEP | |
| SCHEMBL7978138 | 0.81 | KMT2A (0.45) | MEN1KMT2AALDH1A1MMP2ANPEP | |
| SCHEMBL8343803 | 0.77 | KMT2A (0.53) | MEN1KMT2AALDH1A1MMP2ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4912231-A | Reacting a proline derivative with an aromatic nucleophile in presence of a Lewis acid catalyst | E. R. SQUIBB & SONS, INC. (US) | 1990-03-27 | — | — | US | disclosed |