Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.58 |
| ▸ | MMP2 | P08253 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ANPEP | P15144 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | VHL | P40337 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27745576 | 1.00 | KMT2A (0.60) | KMT2AMEN1PIK3CDMMP2ALDH1A1 | |
| SCHEMBL13326445 | 1.00 | KMT2A (0.60) | KMT2AMEN1PIK3CDMMP2ALDH1A1 | |
| SCHEMBL8132886 | 1.00 | KMT2A (0.60) | KMT2AMEN1PIK3CDMMP2ALDH1A1 | |
| SCHEMBL6196388 | 1.00 | KMT2A (0.60) | KMT2AMEN1PIK3CDMMP2ALDH1A1 | |
| SCHEMBL10390327 | 1.00 | KMT2A (0.60) | KMT2AMEN1PIK3CDMMP2ALDH1A1 | |
| SCHEMBL2059306 | 1.00 | KMT2A (0.60) | KMT2AMEN1PIK3CDMMP2ALDH1A1 | |
| SCHEMBL8343803 | 0.92 | KMT2A (0.53) | KMT2AMEN1PIK3CDMMP2ALDH1A1 | |
| SCHEMBL12589771 | 0.89 | PIK3CD (0.56) | KMT2AMEN1PIK3CDMMP2ALDH1A1 | |
| SCHEMBL27957174 | 0.87 | MMP2 (0.60) | KMT2AMEN1PIK3CDMMP2ALDH1A1 | |
| SCHEMBL9311424 | 0.86 | KMT2A (0.53) | KMT2AMEN1MMP2ALDH1A1ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973739-B1 | N-ARYLSULFONAMIDE- AND PYRROLIDINECARBOXYLIC ACID INTERMEDIATES, AND THEIR USE FOR THE PREPARATION OF HERBICIDAL 1,3-DIOXO-1H-PYRROLO[1,2-C]IMIDAZOLE DERIVATIVES | DEGUSSA (DE) | 2005-11-02 | — | — | EP | disclosed |
| US-6664400-B2 | 1-((4-halo-3-sulfonamidophenyl)aminocarbonyl),2-carboxy -pyrrolidine intermediate of given formula | DEGUSSA AG (DE) | 2003-12-16 | — | — | US | disclosed |
| US-20020137946-A1 | N-arylsulfonamide and pyrrolidinecarboxylic acid intermediates, and their use for the preparation of herbicidal 1,3-dioxo-1h-pyrrolo[1,2-c]imidazole derivatives | DEGUSSA AG (DE) | 2002-09-26 | — | — | US | disclosed |
| US-6384234-B1 | HALOGENATION | DEGUSSA AG (DE) | 2002-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020137946-A1 | N-arylsulfonamide and pyrrolidinecarboxylic acid intermediates, and their use for the preparation of herbicidal 1,3-dioxo-1h-pyrrolo[1,2-c]imidazole derivatives | CBR3, CBR1, CLIC1 | KMT2A 2863/4885MEN1 4730/4885PIK3CD 1388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.