Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | ANPEP | P15144 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14682635 | 0.83 | MEN1 (0.42) | KMT2AMEN1MMP2ANPEPALDH1A1 | |
| SCHEMBL1121964 | 0.82 | ANPEP (0.50) | KMT2AMEN1MMP2ANPEPALDH1A1 | |
| SCHEMBL12284558 | 0.82 | ANPEP (0.50) | KMT2AMEN1MMP2ANPEPALDH1A1 | |
| SCHEMBL7979807 | 0.81 | KMT2A (0.54) | KMT2AMEN1HPGDMAPTHTT | |
| SCHEMBL7982334 | 0.81 | KMT2A (0.54) | KMT2AMEN1HPGDMAPTHTT | |
| SCHEMBL10469253 | 0.81 | MEN1 (0.48) | KMT2AMEN1MMP2ANPEPALDH1A1 | |
| SCHEMBL14280062 | 0.81 | KMT2A (0.47) | KMT2AMEN1HPGDALDH1A1KDM4E | |
| SCHEMBL7968263 | 0.80 | KMT2A (0.39) | KMT2AHPGDMMP2ANPEPALDH1A1 | |
| SCHEMBL9310097 | 0.79 | MAPT (0.41) | KMT2AMEN1MMP2ANPEPALDH1A1 | |
| SCHEMBL7985048 | 0.79 | GAA (0.43) | KMT2AMEN1MMP2ANPEPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225306-B1 | PYRROLO(1,2A)QUINOXALINES | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 2001-05-01 | — | — | US | disclosed |