Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | GBA1 | P04062 | 2/20 | 0.54 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.54 |
| ▸ | DTYMK | P23919 | 1/20 | 0.53 |
| ▸ | KIT | P10721 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21714437 | 0.85 | HTR1A (0.49) | HTR1ADRD2HTR2ADRD3HCAR2 | |
| SCHEMBL9203345 | 0.84 | HTR1A (0.74) | HTR1ADRD2HTR2ADRD3HCAR2 | |
| SCHEMBL21633550 | 0.84 | HTR1A (0.47) | HTR1ADRD2HTR2ADRD3GBA1 | |
| SCHEMBL18282626 | 0.82 | POLB (0.51) | GBA1DTYMKKIT | |
| SCHEMBL20025488 | 0.81 | HTR1A (0.44) | HTR1ADRD2HTR2ADRD3GBA1 | |
| SCHEMBL21633611 | 0.79 | GPR119 (0.49) | HTR1ADRD2HTR2ADRD3DTYMK | |
| SCHEMBL3340474 | 0.78 | KIT (0.53) | GBA1DTYMKKIT | |
| SCHEMBL2913962 | 0.77 | GBA1 (0.53) | GBA1DTYMKKIT | |
| SCHEMBL8145185 | 0.76 | KDM4E (0.60) | HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL2918433 | 0.76 | GBA1 (0.56) | GBA1KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4956368-A | Antipsychotic agents | BRISTOL-MYERS COMPANY (US) | 1990-09-11 | — | — | US | disclosed |