Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK2 | Q13002 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | PER2 | O15055 | 1/20 | 0.44 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.44 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9657130 | 0.87 | GRIK2 (0.54) | GRIK2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10469609 | 0.84 | GRIK2 (0.51) | GRIK2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10528703 | 0.80 | KDM4E (0.47) | GRIK2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11374713 | 0.77 | MAPT (0.46) | GRIK2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9626437 | 0.75 | TP53 (0.46) | GRIK2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9626466 | 0.75 | CNR2 (0.53) | GRIK2ALDH1A1GAAKDM4ENPSR1 | |
| SCHEMBL10835469 | 0.75 | ALDH1A1 (0.46) | GRIK2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9657046 | 0.74 | ALDH1A1 (0.52) | GRIK2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9659512 | 0.73 | ALDH1A1 (0.47) | GRIK2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9657071 | 0.72 | KMT2A (0.45) | GRIK2MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920220-A | FOR PRESSURE OR HEAT SENSITIVE RECORDING MATERIALS | CIBA-GEIGY CORPORATION (US) | 1990-04-24 | — | — | US | disclosed |
| EP-0316277-A2 | Chromogeneous 1-heterocyclically substituted 2,4-benzoxazines | CIBA-GEIGY AG (CH) | 1989-05-17 | — | — | EP | disclosed |