Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK2 | Q13002 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSPO | P30536 | 1/20 | 0.45 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10469607 | 0.84 | GRIK2 (0.52) | GRIK2KDM4EMAPK1HTTSMN1; SMN2 | |
| SCHEMBL9657130 | 0.81 | GRIK2 (0.54) | GRIK2KDM4EMAPK1HTTSMN1; SMN2 | |
| SCHEMBL10528703 | 0.76 | KDM4E (0.47) | GRIK2KDM4EMAPK1HTTSMN1; SMN2 | |
| SCHEMBL27846829 | 0.75 | DNM1 (0.70) | KDM4EMAPK1HTTSMN1; SMN2DNM1 | |
| SCHEMBL10835469 | 0.74 | ALDH1A1 (0.46) | GRIK2KDM4EMAPK1HTTCYP19A1 | |
| SCHEMBL9657046 | 0.73 | ALDH1A1 (0.52) | GRIK2KDM4EMAPK1HTTCYP19A1 | |
| SCHEMBL11374713 | 0.71 | MAPT (0.46) | GRIK2KDM4EHTTSMN1; SMN2P2RX4 | |
| SCHEMBL9658406 | 0.71 | MEN1 (0.44) | GRIK2KDM4EHTTSMN1; SMN2CYP19A1 | |
| SCHEMBL7487744 | 0.71 | KDM4E (0.53) | GRIK2KDM4EMAPK1LMNACNR2 | |
| SCHEMBL9626437 | 0.69 | TP53 (0.46) | GRIK2KDM4EMAPK1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920220-A | FOR PRESSURE OR HEAT SENSITIVE RECORDING MATERIALS | CIBA-GEIGY CORPORATION (US) | 1990-04-24 | — | — | US | disclosed |
| EP-0316277-A2 | Chromogeneous 1-heterocyclically substituted 2,4-benzoxazines | CIBA-GEIGY AG (CH) | 1989-05-17 | — | — | EP | disclosed |