Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 4/20 | 0.54 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.53 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3412231 | 0.90 | PRMT5 (0.52) | KCNQ2ANO1PRMT5WDR77TAS1R3 | |
| SCHEMBL10467510 | 0.90 | PRMT5 (0.52) | KCNQ2ANO1PRMT5WDR77TAS1R3 | |
| SCHEMBL31613076 | 0.90 | PRMT5 (0.52) | KCNQ2ANO1PRMT5WDR77TAS1R3 | |
| SCHEMBL19207602 | 0.83 | PIN1 (0.54) | PIN1KCNQ2PDPK1ANO1ROCK1 | |
| SCHEMBL29415781 | 0.83 | PIN1 (0.54) | PIN1KCNQ2PDPK1ANO1ROCK1 | |
| SCHEMBL21016972 | 0.82 | P2RX7 (0.52) | PIN1KCNQ2PDPK1ACKR3 | |
| SCHEMBL28937024 | 0.82 | PIN1 (0.56) | PIN1KCNQ2PDPK1ANO1ROCK1 | |
| SCHEMBL4742598 | 0.80 | PIN1 (0.58) | PIN1KCNQ2PDPK1ANO1TAS1R3 | |
| SCHEMBL8848989 | 0.80 | PIN1 (0.58) | PIN1KCNQ2PDPK1ANO1TAS1R3 | |
| SCHEMBL3591095 | 0.80 | PIN1 (0.51) | PIN1KCNQ2PDPK1ANO1ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4957914-A | ANTIDEPRESSANTS, ANXIOLYTICS, HYPOTENSIVE AGENTS | SYNTEX (U.S.A.) INC. (US) | 1990-09-18 | — | — | US | disclosed |
| US-4013682-A | N-HYDROXY-AMIDINE COMPOUNDS | AKZONA INCORPORATED (US) | 1977-03-22 | — | — | US | disclosed |
| US-3978126-A | N-HYDROXY-AMIDINE COMPOUNDS | AKZONA INCORPORATED (US) | 1976-08-31 | — | — | US | disclosed |