Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 14/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 7/20 | 0.56 |
| ▸ | PTGIS | Q16647 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10471022 | 0.95 | TBXAS1 (0.63) | TBXAS1TBXA2RPTGIS | |
| SCHEMBL10470717 | 0.93 | TBXAS1 (0.67) | TBXAS1TBXA2RPTGIS | |
| SCHEMBL10470715 | 0.89 | TBXAS1 (0.75) | TBXAS1TBXA2RPTGIS | |
| SCHEMBL10471528 | 0.87 | TBXAS1 (0.47) | TBXAS1TBXA2RPTGIS | |
| SCHEMBL10401258 | 0.82 | PDE9A (0.46) | TBXAS1TBXA2RPTGIS | |
| SCHEMBL10470716 | 0.80 | TBXAS1 (0.72) | TBXAS1TBXA2R | |
| SCHEMBL10471495 | 0.80 | TBXAS1 (0.53) | TBXAS1PTGIS | |
| SCHEMBL10562955 | 0.79 | CYP1A2 (0.64) | TBXAS1TBXA2RPTGIS | |
| SCHEMBL10470778 | 0.78 | TBXAS1 (0.75) | TBXAS1TBXA2R | |
| SCHEMBL10471108 | 0.77 | TBXAS1 (0.80) | TBXAS1TBXA2RPTGIS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4921866-A | 1,3-dioxanes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-01 | — | — | US | disclosed |
| EP-0288279-A2 | 1,3-Dioxanes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-10-26 | — | — | EP | disclosed |