Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 17/20 | 0.47 |
| ▸ | PTGIS | Q16647 | 6/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.43 |
| ▸ | PDE9A | O76083 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10471495 | 0.93 | TBXAS1 (0.53) | TBXAS1PTGIS | |
| SCHEMBL10470041 | 0.87 | TBXAS1 (0.59) | TBXAS1PTGISTBXA2R | |
| SCHEMBL10401258 | 0.84 | PDE9A (0.46) | TBXAS1PTGISTBXA2RPDE9A | |
| SCHEMBL10471482 | 0.84 | CYP1A2 (0.49) | TBXAS1PTGISTBXA2RPDE9A | |
| SCHEMBL10471022 | 0.82 | TBXAS1 (0.63) | TBXAS1PTGISTBXA2R | |
| SCHEMBL10471493 | 0.82 | TBXAS1 (0.57) | TBXAS1PTGIS | |
| SCHEMBL10471461 | 0.81 | CYP1A2 (0.61) | TBXAS1TBXA2R | |
| SCHEMBL10470717 | 0.80 | TBXAS1 (0.67) | TBXAS1PTGISTBXA2R | |
| SCHEMBL9671008 | 0.79 | TBXAS1 (0.63) | TBXAS1PTGISTBXA2R | |
| SCHEMBL10401360 | 0.79 | PDE9A (0.47) | TBXAS1PTGISTBXA2RPDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4921866-A | 1,3-dioxanes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-01 | — | — | US | disclosed |
| EP-0288279-A2 | 1,3-Dioxanes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-10-26 | — | — | EP | disclosed |