SCHEMBL104703

SCHEMBL104703

COC(=O)c1ccccc1CBr

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.67
LMNA P02545 2/20 0.67
TSHR P16473 1/20 0.55
HSD17B10 Q99714 2/20 0.53
CFTR P13569 1/20 0.53
KDM4E B2RXH2 2/20 0.52
POLB P06746 2/20 0.52
ATM Q13315 1/20 0.52
KMT2A Q03164 1/20 0.51
HIF1A Q16665 1/20 0.51
GLA P06280 1/20 0.49
HTT P42858 1/20 0.48
SLC6A3 Q01959 2/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA5A P35218 1/20 0.47
CA9 Q16790 1/20 0.47
MAPT P10636 1/20 0.47
ALOX15 P16050 1/20 0.47
GAA P10253 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30945155 1.00 ALDH1A1 (0.67) ALDH1A1LMNATSHRHSD17B10CFTR
SCHEMBL9643936 0.89 ALDH1A1 (0.55) ALDH1A1LMNATSHRHSD17B10CFTR
SCHEMBL27797700 0.87 ALDH1A1 (0.70) ALDH1A1LMNATSHRHSD17B10CFTR
SCHEMBL5284224 0.86 ALDH1A1 (0.55) ALDH1A1LMNATSHRHSD17B10CFTR
SCHEMBL1918904 0.85 ALDH1A1 (0.68) ALDH1A1LMNATSHRHSD17B10CFTR
SCHEMBL31567935 0.85 ALDH1A1 (0.68) ALDH1A1LMNATSHRHSD17B10CFTR
SCHEMBL70322 0.84 ALDH1A1 (0.66) ALDH1A1LMNATSHRHSD17B10CFTR
SCHEMBL10360804 0.84 ALDH1A1 (0.77) ALDH1A1LMNATSHRHSD17B10CFTR
SCHEMBL156281 0.84 ALDH1A1 (0.66) ALDH1A1LMNATSHRHSD17B10CFTR
SCHEMBL491271 0.84 ALDH1A1 (0.47) ALDH1A1LMNATSHRKDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118619922-A Hydroxamic acid compound, and preparation method and application thereof 郑州大学 2024-09-10 CN claimed
WO-2023061101-A1 HDAC/MAO-B DUAL INHIBITOR, PREPARATION THEREOF, AND APPLICATION THEREOF 杭州师范大学 2023-04-20 WO claimed
CN-113214521-B Proton exchange membrane and preparation method thereof 上海鑫珀生物科技有限公司 2023-04-18 CN claimed
CN-110526856-B Synthetic method of DWP205190 天津瑞岭化工有限公司 2023-04-07 CN claimed
CN-114989141-A Lenalidomide derivative and preparation method and application thereof 济南爱思医药科技有限公司 2022-09-02 CN claimed
CN-114621194-A 4-methylene-N-hydroxybenzamide compound and application thereof 沈阳药科大学 2022-06-14 CN claimed
CN-113214521-A Proton exchange membrane and preparation method thereof 上海鑫珀生物科技有限公司 2021-08-06 CN claimed
CN-110818713-A Matrine α -ketoamine compound and preparation method and application thereof 上海星叶医药科技有限公司 2020-02-21 CN claimed
CN-110498759-A The synthetic method of isoindoline ketone compound TIANJIN RUILING CHEMICAL CO LTD 2019-11-26 CN claimed
WO-2019196369-A1 THIAZOLO-PYRIMIDINE HIV-1 REVERSE TRANSCRIPTASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USES THEREOF 山东大学 2019-10-17 WO claimed
CN-108218896-A A kind of Thiazolopyrimidine HIV-1 reverse transcriptase inhibitor and its preparation method and application 山东大学 2018-06-29 CN claimed
CN-105111214-B A kind of preparation method of pemetrexed disodium 江西农业大学 2017-10-31 CN claimed
CN-106928092-A The preparation method of one inter-species cyanogen methyl toluate 上海微巨实业有限公司 2017-07-07 CN claimed
CN-102040603-B The purposes of the adjacent methoxycarbonyl benzyl tetrahydro Berberine of bromination N-and treatment hyperlipidemia thereof INSTITUTE OF MATARIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2016-01-06 CN claimed
CN-105111214-A Preparation method of pemetrexed disodium UNIV JIANGXI AGRICULTURAL 2015-12-02 CN claimed
CN-102532029-A Selective ionic liquid, synthesis method, and application thereof UNIV BEIJING TECHNOLOGY 2012-07-04 CN claimed
CN-102040603-A Brominated N-o-methoxycarbonylbenzyl tetrahydroberberine and application thereof in treatment of hyperlipidemia INST MATERIA MEDICA CAMS 2011-05-04 CN claimed
CN-101036894-B Preparing method and application of chiral imidazolinone fungicide decorated by peptide loded with silica gel UNIV EAST CHINA NORMAL 2010-09-08 CN claimed
CN-101036894-A Preparing method and application of chiral imidazolinone fungicide decorated by peptide loded with silica gel UNIV EAST CHINA NORMAL (CN) 2007-09-19 CN claimed
WO-2006021974-A1 A PROCESS FOR SYNTHESIZING DIOL (VIII)-AN INTERMEDIATE OF MONTELUKAST SODIUM MOREPEN LABORATORIES LIMITED (IN) 2006-03-02 WO claimed