SCHEMBL491271

SCHEMBL491271

O=C(OOC(=O)c1ccccc1CBr)c1ccccc1CBr

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
LMNA P02545 2/20 0.47
F2 P00734 1/20 0.41
TSHR P16473 4/20 0.41
KMT2A Q03164 1/20 0.40
SCN1A P35498 2/20 0.38
SCN2A Q99250 2/20 0.38
SCN3A Q9NY46 2/20 0.38
NPC1 O15118 1/20 0.37
FOLH1 Q04609 1/20 0.37
CYP3A4 P08684 1/20 0.37
HIF1A Q16665 1/20 0.36
TDP1 Q9NUW8 2/20 0.36
PTPN1 P18031 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KDM4E B2RXH2 1/20 0.36
GLA P06280 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2727814 0.86 ALDH1A1 (0.46) ALDH1A1LMNATSHRKMT2ASCN1A
SCHEMBL30945155 0.84 ALDH1A1 (0.67) ALDH1A1LMNATSHRKMT2AHIF1A
SCHEMBL104703 0.84 ALDH1A1 (0.67) ALDH1A1LMNATSHRKMT2AHIF1A
SCHEMBL4587694 0.82 ALDH1A1 (0.37) ALDH1A1LMNAF2TSHRKMT2A
SCHEMBL16534733 0.82 ALDH1A1 (0.38) ALDH1A1LMNATSHRKMT2ASCN1A
SCHEMBL980123 0.81 HSD17B10 (0.58) ALDH1A1LMNATSHRKMT2ACYP3A4
SCHEMBL1468126 0.81 TSHR (0.69) ALDH1A1LMNATSHRKMT2ASCN1A
SCHEMBL19500120 0.81 NPC1 (0.51) ALDH1A1LMNATSHRKMT2ASCN1A
SCHEMBL6464901 0.81 TSHR (0.52) ALDH1A1LMNAF2TSHRSCN1A
SCHEMBL3135339 0.80 FOLH1 (0.41) ALDH1A1LMNATSHRFOLH1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 305 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7652128-B2 Toner composition XEROX CORPORATION (US) 2010-01-26 US claimed
US-20090142692-A1 LOW MOLECULAR WEIGHT LATEX AND TONER COMPOSITIONS COMPRISING THE SAME XEROX CORPORATION (US) 2009-06-04 US claimed
US-20060286476-A1 manufactured under monomer-starved polymerization condition such as monomer feeding rate equal to or less than 0.516% per minute by weight of the monomer(s) to be fed; gloss, fusing performance, crease performance, stripping performance, document offset, vinyl offset, and parent charging etc. XEROX CORPORATION 2006-12-21 US claimed
US-20060100300-A1 Toner composition XEROX CORPORATION 2006-05-11 US claimed
EP-4045544-B1 SUPER ADVANCED CONTROLLED RADICAL POLYMERIZATION BASF COATINGS GMBH (DE) 2026-03-18 EP disclosed
US-12578664-B2 Toner and method for producing toner CANON KABUSHIKI KAISHA (JP) 2026-03-17 US disclosed
US-12534561-B2 Controlled radical polymerization BASF COATINGS GMBH (DE) 2026-01-27 US disclosed
US-12510839-B2 Process cartridge and process cartridge set CANON KABUSHIKI KAISHA (JP) 2025-12-30 US disclosed
US-20250298331-A1 TONER CANON KABUSHIKI KAISHA (JP) 2025-09-25 US disclosed
US-20250284233-A1 IMAGE FORMING SYSTEM Konica Minolta, Inc. (JP) 2025-09-11 US disclosed
US-12393131-B2 Toner CANON KABUSHIKI KAISHA (JP) 2025-08-19 US disclosed
US-20250181004-A1 PROCESS CARTRIDGE AND PROCESS CARTRIDGE SET CANON KABUSHIKI KAISHA (JP) 2025-06-05 US disclosed
US-20040191663-A1 Non-magnetic one-component toner, non-magnetic one-component contact developing device and image-forming apparatus MINOLTA CO., LTD. 2004-09-30 US disclosed
US-20040152004-A1 Toner having specific relation between absorption soectra, and developer, image forming method and image forming apparatus using same FUJI XEROX CO., LTD. (JP) 2004-08-05 US disclosed
US-20040146315-A1 Image-forming method and image-forming apparatus MINOLTA CO., LTD. 2004-07-29 US disclosed
US-20040067429-A1 Electrostatic-latent-image developing toner MINOLTA CO., LTD. 2004-04-08 US disclosed
US-6607864-B2 Heating heating member that is in contact with a toner image to fix toner image onto a recording medium, wherein a surface of heating member or vicinity generates heat, and a toner forming the toner image contains a colorant and binder resin FUJI XEROX CO., LTD. (JP) 2003-08-19 US disclosed
US-6582867-B2 A crystalline binder resin and a fatty acid ester or a resin having a contact angle with water that is smaller than that of the crystalline resin; electrography; reproducibility in particle size/distribution; low-temperature fixing; stability FUJI XEROX CO., LTD. (JP) 2003-06-24 US disclosed
US-20030027073-A1 Image forming method FUJI XEROX CO., LTD. (JP) 2003-02-06 US disclosed
US-20020055050-A1 Toner for developing electrostatic latent image, process for producing the same, and process for forming image FUJI XEROX CO., LTD. (JP) 2002-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534561-B2 Controlled radical polymerization TST, G6PD, PROC ALDH1A1 193/4885LMNA 2883/4885F2 532/4885
US-12510839-B2 Process cartridge and process cartridge set C1R, NRAS, C1S ALDH1A1 3533/4885LMNA 426/4885F2 218/4885
US-12578664-B2 Toner and method for producing toner C1R, TECR, FCGR2A ALDH1A1 4329/4885LMNA 1225/4885F2 2144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.