SCHEMBL10470441

SCHEMBL10470441

COc1cccc(Cc2ccccc2O)c1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.62
MAPT P10636 3/20 0.62
TP53 P04637 2/20 0.62
KDM4E B2RXH2 2/20 0.62
LMNA P02545 2/20 0.62
HPGD P15428 2/20 0.62
CYP3A4 P08684 1/20 0.62
ALOX15 P16050 1/20 0.62
ALOX12 P18054 1/20 0.62
MAPK1 P28482 1/20 0.62
HSD17B10 Q99714 1/20 0.62
CALM1 P0DP23 1/20 0.59
HSPA5 P11021 1/20 0.57
IDO1 P14902 1/20 0.56
ALOX5 P09917 2/20 0.54
PTGS2 P35354 1/20 0.54
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
TSHR P16473 1/20 0.53
MPO P05164 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10987745 0.87 HSPA5 (0.64) ALDH1A1MAPTTP53KDM4ELMNA
SCHEMBL9771763 0.82 CALM1 (0.69) ALDH1A1MAPTTP53KDM4ELMNA
SCHEMBL14272185 0.82 CALM1 (0.59) ALDH1A1MAPTTP53KDM4ELMNA
SCHEMBL5852506 0.80 HSPA5 (0.80) ALDH1A1LMNAHPGDALOX15HSD17B10
SCHEMBL54577 0.80 HSPA5 (0.80) ALDH1A1LMNAHPGDALOX15HSD17B10
SCHEMBL30874252 0.80 HSPA5 (0.80) ALDH1A1LMNAHPGDALOX15HSD17B10
SCHEMBL10470235 0.80 CALM1 (0.54) ALDH1A1MAPTTP53KDM4ELMNA
SCHEMBL8583175 0.78 HSPA5 (0.76) ALDH1A1LMNAHPGDALOX15HSD17B10
3-Methoxycatechol SCHEMBL67332 0.78 TP53 (1.00) ALDH1A1MAPTTP53KDM4ELMNA
3-Methoxycatechol SCHEMBL29477155 0.78 TP53 (1.00) ALDH1A1MAPTTP53KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4979978-A Herbicidal 12H-dibenzo[d,g][1,3]dioxocin-6-carboxylic acids THE DOW CHEMICAL COMPANY (US) 1990-12-25 US disclosed