SCHEMBL54577

SCHEMBL54577

Oc1ccccc1Cc1cccc(Cc2ccccc2O)c1O

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.80
KEAP1 Q14145 1/20 0.56
CYP2D6 P10635 1/20 0.50
TSHR P16473 1/20 0.50
HIF1A Q16665 1/20 0.50
TAAR1 Q96RJ0 1/20 0.48
AKR1B1 P15121 1/20 0.48
GABRA1 P14867 1/20 0.48
GABRB2 P47870 1/20 0.48
CA2 P00918 4/20 0.46
CA12 O43570 3/20 0.46
IDO1 P14902 2/20 0.46
ADAMTS4 O75173 1/20 0.46
ALDH1A1 P00352 1/20 0.46
EGFR P00533 1/20 0.46
CA1 P00915 1/20 0.46
LMNA P02545 1/20 0.46
FYN P06241 1/20 0.46
MMP2 P08253 1/20 0.46
MMP9 P14780 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5852506 1.00 HSPA5 (0.80) HSPA5KEAP1CYP2D6TSHRHIF1A
SCHEMBL30874252 1.00 HSPA5 (0.80) HSPA5KEAP1CYP2D6TSHRHIF1A
SCHEMBL8583175 0.93 HSPA5 (0.76) HSPA5KEAP1CYP2D6TSHRHIF1A
SCHEMBL14595234 0.91 HSPA5 (0.67) HSPA5KEAP1CYP2D6TSHRHIF1A
SCHEMBL11686142 0.91 HSPA5 (0.67) HSPA5KEAP1CYP2D6TSHRHIF1A
SCHEMBL4064773 0.89 HSPA5 (0.64) HSPA5KEAP1CYP2D6TSHRHIF1A
SCHEMBL29357407 0.89 HSPA5 (1.00) HSPA5KEAP1CYP2D6TSHRHIF1A
SCHEMBL49745 0.89 HSPA5 (1.00) HSPA5KEAP1CYP2D6TSHRHIF1A
SCHEMBL13256353 0.88 HSPA5 (0.61) HSPA5KEAP1CYP2D6TSHRHIF1A
SCHEMBL17666372 0.88 HSPA5 (0.61) HSPA5KEAP1CYP2D6TSHRHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5340888-A Curable mixture of phenolic novolak resin, esterified phenolic compound and base; for foundry molds, cores BORDEN INC. (US) 1994-08-23 US claimed
US-4055546-A REACTION OF A PHENOLIC RESIN WITH AN ORGANIC SILICATE HITACHI CHEMICAL COMPANY, LTD. (JA) 1977-10-25 US claimed
US-3950309-A MOLDING MATERIALS HITACHI CHEMICAL CO., LTD. (JA) 1976-04-13 US claimed
US-20260062580-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT THE PILOT INK CO., LTD. (JP) 2026-03-05 US disclosed
EP-4703428-A1 CONDUCTIVE RESIN COMPOSITION Sakata INX Corporation (JP) 2026-03-04 EP disclosed
EP-3954745-B1 REVERSIBLY THERMOCHROMIC AQUEOUS INK COMPOSITION FOR WRITING UTENSILS, AND REFILL AND WATER-BASED BALLPOINT PEN EACH INTERNALLY CONTAINING SAME KK PILOT CORPORATION ALSO TRADING AS PILOT CORPORATION (JP) 2026-01-07 EP disclosed
US-12460099-B2 Reversibly thermochromic composition, reversibly thermochromic microcapsule pigment encapsulating reversibly thermochromic composition, and writing instrument using reversibly thermochromic microcapsule pigment THE PILOT INK CO., LTD. (JP) 2025-11-04 US disclosed
US-12421411-B2 Aqueous ink composition for reversibly thermochromic writing instrument, and refill and aqueous ballpoint pen incorporating aqueous ink composition for reversibly thermochromic writing instrument KABUSHIKI KAISHA PILOT CORPORATION (JP) 2025-09-23 US disclosed
US-20240417532-A1 CONDUCTIVE RESIN COMPOSITION SAKATA INX CORPORATION (JP) 2024-12-19 US disclosed
WO-2024224871-A1 CONDUCTIVE RESIN COMPOSITION サカタインクス株式会社 2024-10-31 WO disclosed
EP-4424769-A1 CONDUCTIVE RESIN COMPOSITION Sakata INX Corporation (JP) 2024-09-04 EP disclosed
US-6998182-B2 Organic luminescence device CANON KABUSHIKI KAISHA (JP) 2006-02-14 US disclosed
US-20030232216-A1 Organic luminescence device CANON KABUSHIKI KAISHA 2003-12-18 US disclosed
WO-2003029383-A1 ORGANIC LUMINESCENCE DEVICE CANON KABUSHIKI KAISHA (JP) 2003-04-10 WO disclosed
US-5372917-A Excellent color forming property, storage stability and recorded image preservability; pyrazolone derivatives KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1994-12-13 US disclosed
US-4282390-A PARASITICIDES ICI AUSTRALIA LIMITED (AU) 1981-08-04 US disclosed
US-4163801-A PARASITICIDES, NEMATOCIDES ICI AUSTRALIA LIMITED (AU) 1979-08-07 US disclosed
US-4163801-A PARASITICIDES, NEMATOCIDES ICI AUSTRALIA LIMITED (AU) 1979-08-07 US disclosed
US-4055546-A REACTION OF A PHENOLIC RESIN WITH AN ORGANIC SILICATE HITACHI CHEMICAL COMPANY, LTD. (JA) 1977-10-25 US disclosed
US-3950309-A MOLDING MATERIALS HITACHI CHEMICAL CO., LTD. (JA) 1976-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062580-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT TYR, SCO2, HBB HSPA5 3280/4885KEAP1 2421/4885CYP2D6 1681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.