Diphenylsulfane

Diphenylsulfane

SCHEMBL1047048

CCCCOc1ccc(CCl)cc1.c1ccc(Sc2ccccc2)cc1

nearest known ligand 0.53

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.53
TSHR P16473 1/20 0.44
CHRNA7 P36544 2/20 0.43
CHRNB4 P30926 1/20 0.43
CHRNA3 P32297 1/20 0.43
ALOX5 P09917 1/20 0.43
PPARG P37231 1/20 0.43
PPARA Q07869 1/20 0.43
CYP2D6 P10635 2/20 0.42
CYP3A4 P08684 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP19A1 P11511 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12429524 0.87 LTA4H (0.63) LTA4HTSHRCHRNA7CHRNB4CHRNA3
SCHEMBL9502090 0.85 LMNA (0.45) LTA4HTSHRCYP2C19L3MBTL1
SCHEMBL2995440 0.85 TSHR (0.56) LTA4HTSHRCYP2D6CYP3A4CYP1A2
Diphenylsulfane SCHEMBL1045379 0.84 LTA4H (0.53) LTA4HCHRNA7CHRNB4CHRNA3ALOX5
SCHEMBL23628116 0.82 LTA4H (0.64) LTA4HTSHRCYP3A4
SCHEMBL21065248 0.82 LTA4H (0.64) LTA4HTSHRCYP3A4
SCHEMBL13105274 0.82 LTA4H (0.64) LTA4HTSHRCYP3A4
SCHEMBL16195385 0.82 LTA4H (0.64) LTA4HTSHRCYP3A4
SCHEMBL6018241 0.81 NR5A1 (0.58) LTA4HTSHR
SCHEMBL1046791 0.81 LTA4H (0.53) LTA4HTSHRCYP2D6CYP1A2CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8450231-B2 Silicon-containing particles, method for manufacturing thereof, oil composition, ceramic material, and method for manufacturing thereof DOW CORNING TORAY COMPANY, LTD. (JP) 2013-05-28 US disclosed
EP-2461397-A1 ELECTRODE ACTIVE MATERIAL, ELECTRODE, AND ELECTRICITY STORAGE DEVICE Dow Corning Toray Co., Ltd. (JP) 2012-06-06 EP disclosed
US-20110045963-A1 Silicon-Containing Particles, Method For Manufacturing Thereof, Oil Composition, Ceramic Material, And Method For Manufacturing Thereof DOW CORNING TORAY COMPANY, LTD. (JP) 2011-02-24 US disclosed
EP-2271702-A2 SILICON-CONTAINING PARTICLES, METHOD FOR MANUFACTURING THEREOF, OIL COMPOSITION, CERAMIC MATERIAL, AND METHOD FOR MANUFACTURING THEREOF Dow Corning Toray Co., Ltd. (JP) 2011-01-12 EP disclosed
EP-2241586-A1 SILICON-CONTAINING PARTICLE, PROCESS FOR PRODUCING THE SAME, ORGANIC-POLYMER COMPOSITION, CERAMIC, AND PROCESS FOR PRODUCING THE SAME Dow Corning Toray Co., Ltd. (JP) 2010-10-20 EP disclosed
WO-2009133765-A2 SILICON-CONTAINING PARTICLES, METHOD FOR MANUFACTURING THEREOF, OIL COMPOSITION, CERAMIC MATERIAL, AND METHOD FOR MANUFACTURING THEREOF DOW CORNING TORAY CO., LTD. (JP) 2009-11-05 WO disclosed