SCHEMBL10470671

SCHEMBL10470671

COC(=O)c1ccc(Cc2cn(C(C)C)c3ccc(C=C(C)C(=O)OC(C)(C)C)cc23)c(OC)c1

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PLA2G4A P47712 14/20 0.46
LTB4R Q15722 5/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10470666 1.00 PLA2G4A (0.46) PLA2G4ALTB4R
SCHEMBL10470670 1.00 PLA2G4A (0.46) PLA2G4ALTB4R
SCHEMBL9376345 0.93 PLA2G4A (0.54) PLA2G4ALTB4R
SCHEMBL9376333 0.93 PLA2G4A (0.54) PLA2G4ALTB4R
SCHEMBL9376341 0.93 PLA2G4A (0.54) PLA2G4ALTB4R
SCHEMBL9757600 0.91
SCHEMBL9757585 0.91
SCHEMBL9757594 0.91
SCHEMBL9372863 0.89 PLA2G4A (0.51) PLA2G4ALTB4R
SCHEMBL9372866 0.89 PLA2G4A (0.51) PLA2G4ALTB4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4894386-A ANTIINFLAMMATORY AGENTS ICI AMERICAS INC. (US) 1990-01-16 US disclosed