⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757585 | 1.00 | — | — | |
| SCHEMBL9757594 | 1.00 | — | — | |
| SCHEMBL9374408 | 0.92 | PLA2G4A (0.48) | — | |
| SCHEMBL9374394 | 0.92 | PLA2G4A (0.48) | — | |
| SCHEMBL9374404 | 0.92 | PLA2G4A (0.48) | — | |
| SCHEMBL10470671 | 0.91 | PLA2G4A (0.46) | — | |
| SCHEMBL10470670 | 0.91 | PLA2G4A (0.46) | — | |
| SCHEMBL10470666 | 0.91 | PLA2G4A (0.46) | — | |
| SCHEMBL10469310 | 0.90 | CYSLTR2 (0.48) | — | |
| SCHEMBL10469312 | 0.90 | CYSLTR2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041460-A | Antiallergens, antiinflammatory agents and leukotriene antagonists | ICI AMERICAS INC. (US) | 1991-08-20 | — | — | US | disclosed |
| US-4894386-A | ANTIINFLAMMATORY AGENTS | ICI AMERICAS INC. (US) | 1990-01-16 | — | — | US | disclosed |
| EP-0337766-A1 | Hetera-aliphatic carboxamides | ICI AMERICAS INC. (US) | 1989-10-18 | — | — | EP | disclosed |