Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 16/20 | 0.66 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.66 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1047070 | 1.00 | PTGFR (0.66) | PTGFRPTGER3TRPA1MEN1ALDH1A1 | |
| SCHEMBL1047071 | 1.00 | PTGFR (0.66) | PTGFRPTGER3TRPA1MEN1ALDH1A1 | |
| SCHEMBL1045489 | 0.90 | PTGFR (0.54) | PTGFRPTGER3TRPA1MEN1ALDH1A1 | |
| SCHEMBL1045486 | 0.90 | PTGFR (0.54) | PTGFRPTGER3TRPA1MEN1ALDH1A1 | |
| SCHEMBL1045487 | 0.90 | PTGFR (0.54) | PTGFRPTGER3TRPA1MEN1ALDH1A1 | |
| SCHEMBL1047115 | 0.90 | PTGFR (0.54) | PTGFRPTGER3TRPA1MEN1ALDH1A1 | |
| SCHEMBL3342993 | 0.90 | PTGFR (0.68) | PTGFRPTGER3TRPA1MEN1ALDH1A1 | |
| SCHEMBL1045457 | 0.90 | PTGFR (0.68) | PTGFRPTGER3TRPA1MEN1ALDH1A1 | |
| SCHEMBL1047117 | 0.90 | PTGFR (0.54) | PTGFRPTGER3TRPA1MEN1ALDH1A1 | |
| SCHEMBL1045458 | 0.90 | PTGFR (0.68) | PTGFRPTGER3TRPA1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110002866-A1 | METHODS TO PREVENT A HAIR-RELATED SIDE EFFECT OF TREATMENT WITH A CHEMOTHERAPEUTIC AGENT | LUBIT BEVERLY W | 2011-01-06 | — | — | US | claimed |
| US-20100074857-A1 | COMPOSITIONS AND METHODS TO TREAT EPITHELIAL-RELATED CONDITIONS | LIPKIN PAMELA | 2010-03-25 | — | — | US | claimed |
| US-20110002866-A1 | METHODS TO PREVENT A HAIR-RELATED SIDE EFFECT OF TREATMENT WITH A CHEMOTHERAPEUTIC AGENT | LUBIT BEVERLY W | 2011-01-06 | — | — | US | disclosed |
| US-20100074857-A1 | COMPOSITIONS AND METHODS TO TREAT EPITHELIAL-RELATED CONDITIONS | LIPKIN PAMELA | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110002866-A1 | METHODS TO PREVENT A HAIR-RELATED SIDE EFFECT OF TREATMENT WITH A CHEMOTHERAPEUTIC AGENT | PGF, PTGS1, PTGS2 | PTGFR 5/4885PTGER3 75/4885TRPA1 3869/4885 |
| US-20100074857-A1 | COMPOSITIONS AND METHODS TO TREAT EPITHELIAL-RELATED CONDITIONS | PTGER1, PGF, PTGER2 | PTGFR 6/4885PTGER3 9/4885TRPA1 1588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.