Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 8/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27683944 | 0.79 | GPR35 (0.40) | GPR35CYSLTR2CYSLTR1KDM4E | |
| SCHEMBL9163251 | 0.75 | STING1 (0.58) | GLASTING1GPR35CYP2D6KDM4E | |
| SCHEMBL8117421 | 0.72 | GPR35 (0.46) | GPR35CYP2D6CYSLTR2CYSLTR1KDM4E | |
| SCHEMBL7082942 | 0.70 | CYP2D6 (0.52) | CYP2D6CYSLTR2CYSLTR1 | |
| SCHEMBL7082924 | 0.70 | CYP2D6 (0.52) | CYP2D6CYSLTR2CYSLTR1 | |
| Mitoflaxone SCHEMBL106705 | 0.70 | CYP1A2 (0.62) | GLASTING1CYP2D6CYSLTR1KDM4E | |
| SCHEMBL10966059 | 0.70 | MAOB (0.47) | GPR35CYP2D6CYSLTR2CYSLTR1RECQL | |
| SCHEMBL8121513 | 0.70 | GPR35 (0.49) | GPR35CYP2D6KDM4ERECQL | |
| SCHEMBL28290284 | 0.69 | GPR35 (0.59) | GPR35KDM4E | |
| SCHEMBL7087329 | 0.69 | CYP1A2 (0.56) | GLASTING1CYP2D6CYSLTR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4904690-A | Chromone derivatives useful as antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-02-27 | — | — | US | disclosed |
| EP-0283761-A1 | Chromone derivatives | Takeda Chemical Industries, Ltd. (JP) | 1988-09-28 | — | — | EP | disclosed |