Mitoflaxone

Mitoflaxone

SCHEMBL106705

O=C(O)Cc1cccc2c(=O)cc(-c3ccccc3)oc12

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 8/20 0.62
CYP3A4 P08684 5/20 0.62
CYP2D6 P10635 3/20 0.62
CYP2C19 P33261 3/20 0.62
STAT6 P42226 1/20 0.62
CYP1B1 Q16678 8/20 0.56
CYP1A1 P04798 7/20 0.56
CYP19A1 P11511 5/20 0.56
HPGD P15428 4/20 0.56
TP53 P04637 3/20 0.56
ALDH1A1 P00352 3/20 0.56
MAPT P10636 3/20 0.56
KDM4E B2RXH2 2/20 0.56
MAPK1 P28482 2/20 0.56
HSD17B10 Q99714 2/20 0.56
ABCB1 P08183 2/20 0.56
ABCG2 Q9UNQ0 2/20 0.56
CYP2C9 P11712 2/20 0.56
PDE5A O76074 1/20 0.56
TSHR P16473 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12835503 0.97 CYP1A2 (0.60) CYP1A2CYP3A4CYP2D6CYP2C19STAT6
SCHEMBL12835338 0.91 TDP1 (0.57) CYP1A2CYP3A4CYP2D6CYP2C19STAT6
SCHEMBL7085634 0.90 CYP2D6 (0.53) CYP1A2CYP3A4CYP2D6CYP2C19STAT6
SCHEMBL12835324 0.90 TNKS (0.59) CYP1A2CYP3A4CYP2D6CYP2C19STAT6
SCHEMBL12835627 0.90 CYP2D6 (0.58) CYP1A2CYP3A4CYP2D6CYP2C19STAT6
SCHEMBL7087329 0.90 CYP1A2 (0.56) CYP1A2CYP3A4CYP2D6CYP2C19STAT6
SCHEMBL12835505 0.90 CYP1A2 (0.56) CYP1A2CYP3A4CYP2D6CYP2C19STAT6
SCHEMBL9327900 0.90 CYP1A2 (0.56) CYP1A2CYP3A4CYP2D6CYP2C19STAT6
SCHEMBL12835629 0.89 CYP2D6 (0.53) CYP1A2CYP3A4CYP2D6CYP2C19STAT6
SCHEMBL9328614 0.89 CYP1A2 (0.59) CYP1A2CYP3A4CYP2D6CYP2C19STAT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 491 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260048022-A1 ENDOTHELIAL DAMAGE AND NANOPARTICLE TARGETING: COMPOSITIONS, PROCESSES, USES NANOPROBES INC (US) 2026-02-19 US claimed
US-20250188143-A1 COMBINED GENE AND RADIO THERAPY FOR THE TREATMENT OF CANCER FUNDACION PARA LA INVESTIGACION MEDICA APLICADA (ES) 2025-06-12 US claimed
US-20250186623-A1 EXPRESSION SYSTEM FOR THE TREATMENT OF CANCER FUNDACION PARA LA INVESTIGACION MEDICA APLICADA (ES) 2025-06-12 US claimed
EP-4525834-A1 ENDOTHELIAL DAMAGE AND NANOPARTICLE TARGETING: COMPOSITIONS, PROCESSES, USES Nanoprobes, Inc. (US) 2025-03-26 EP claimed
CN-119386177-A Multifunctional coordination polymer for activating hyperthermia induced in-situ vaccine and preparation method and application thereof 中国药科大学 2025-02-07 CN claimed
EP-4489794-A1 COMBINED GENE AND RADIO THERAPY FOR THE TREATMENT OF CANCER Fundación para la Investigación Médica Aplicada (ES) 2025-01-15 EP claimed
EP-4489795-A1 EXPRESSION SYSTEM FOR THE TREATMENT OF CANCER Fundación para la Investigación Médica Aplicada (ES) 2025-01-15 EP claimed
US-20240423927-A1 COMPOSITIONS AND METHODS FOR USE IN IMMUNOTHERAPY INSTITUT CURIE (FR) 2024-12-26 US claimed
CN-119173281-A Expression system for treating cancer 应用医学研究基金会 2024-12-20 CN claimed
CN-119110733-A Gene and radiation combination therapy for the treatment of cancer 应用医学研究基金会 2024-12-10 CN claimed
US-20010041687-A1 Use of flavone 8-acetic acid in vascular and cardiovascular interventions and acute coronary syndromes MRUK JOZEF S (US) 2001-11-15 US claimed
WO-2001052839-A1 USE OF FLAVONE 8-ACETIC ACID IN VASCULAR AND CARDIOVASCULAR INTERVENTIONS AND ACUTE CORONARY SYNDROMES MRUK JOZEF S (US) 2001-07-26 WO claimed
US-6071509-A ADMINISTERING INTERLEUKIN, INTERFERON, OR FLAVONOID MAXIM PHARMACEUTICALS, INC. (US) 2000-06-06 US claimed
US-6063373-A ANTICARCER AGENT MAXIM PHARMACEUTICALS, INC. (US) 2000-05-16 US claimed
US-5585243-A SEPARATELY INCUBATING HUMAN PLATELETS WITH BLOOD SAMPLE ANDREAGENT DRUG SOLUTION TO FORM COMPLEXES, DETERMINING AMOUNT OF BOUND ANTIBODY THE BLOOD CENTER OF SOUTHEASTERN WISCONSIN, INC. (US) 1996-12-17 US claimed
WO-1995008116-A1 METHOD OF DETECTING CYTOPENIA THAT IS MEDIATED BY DRUG-DEPENDENT ANTIBODY BINDING TO BLOOD CELLS THE BLOOD CENTER OF SOUTHEASTERN WISCONSIN, INC. (US) 1995-03-23 WO claimed
EP-0359347-B1 COVALENTLY-LINKED COMPLEXES AND METHODS FOR ENHANCED CYTOTOXICITY AND IMAGING NEORX CORPORATION (US) 1992-12-23 EP claimed
US-5096707-A Reanl carcinoma THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1992-03-17 US claimed
US-5061488-A Flavone-8-acetic acid and interleukin-2 for cancer therapy THE UNITED STATES OF AMERICA AS REPRESENTED DEPARTMENT OF HEALTH & HUMAN SERVICES (US) 1991-10-29 US claimed
EP-0359347-A2 Covalently-linked complexes and methods for enhanced cytotoxicity and imaging NEORX CORPORATION (US) 1990-03-21 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260048022-A1 ENDOTHELIAL DAMAGE AND NANOPARTICLE TARGETING: COMPOSITIONS, PROCESSES, USES VEGFA, FLT1, FLT4 CYP1A2 3120/4885CYP3A4 1873/4885CYP2D6 3235/4885
US-20010041687-A1 Use of flavone 8-acetic acid in vascular and cardiovascular interventions and acute coronary syndromes F8, PLAT, MMP8 CYP1A2 523/4885CYP3A4 1167/4885CYP2D6 808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.