Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.65 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.65 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | APEX1 | P27695 | 2/20 | 0.64 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3021293 | 0.82 | CHRM2 (0.50) | CHRM2CHRM5CHRM1CHRM3CYP2D6 | |
| SCHEMBL12004137 | 0.82 | CHRM2 (0.67) | CHRM2CHRM5CHRM1CHRM3CYP2D6 | |
| SCHEMBL9468715 | 0.80 | CHRM2 (0.65) | CHRM2CHRM5CHRM1CHRM3CYP2D6 | |
| SCHEMBL9029739 | 0.78 | CHRM2 (0.68) | CHRM2CHRM5CHRM1CHRM3CYP2D6 | |
| Oxotremorine SCHEMBL2128 | 0.78 | CHRM2 (1.00) | CHRM2CHRM5CHRM1CHRM3CYP2D6 | |
| Hydrochloric Acid SCHEMBL7371622 | 0.78 | CHRM2 (0.62) | CHRM2CHRM5CHRM1CHRM3CYP2D6 | |
| SCHEMBL31263727 | 0.78 | CHRM2 (0.93) | CHRM2CHRM5CHRM1CHRM3CYP2D6 | |
| SCHEMBL11725908 | 0.78 | CHRM2 (0.62) | CHRM2CHRM5CHRM1CHRM3CYP2D6 | |
| Oxotremorine SCHEMBL1320883 | 0.78 | CHRM2 (0.90) | CHRM2CHRM5CHRM1CHRM3CYP2D6 | |
| SCHEMBL4542695 | 0.78 | CHRM2 (1.00) | CHRM2CHRM5CHRM1CHRM3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825155-B2 | Oxindole derivative as feeding control agent | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2010-11-02 | — | — | US | disclosed |
| US-20090131398-A1 | OXINDOLE DERIVATIVE AS FEEDING CONTROL AGENT | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-05-21 | — | — | US | disclosed |
| US-4916139-A | TREATMENT OF CONVULSIONS, DEPRESSION, HYPERTENSION, PAIN | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1990-04-10 | — | — | US | disclosed |
| EP-0333026-A1 | 3-(2,3,4,5,6-Pentafluorophenoxy)-8-azabicyclo[3.2.1]octanes, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1989-09-20 | — | — | EP | disclosed |
| US-4861889-A | 3-(2,3,4,5,6-pentafluorophenoxy)-8-azabicyclo[3.2.1]octanes | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1989-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131398-A1 | OXINDOLE DERIVATIVE AS FEEDING CONTROL AGENT | GPR119, OXTR, CCKAR | CHRM2 151/4885CHRM5 314/4885CHRM1 95/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.