Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR1 | Q04771 | 2/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | FER | P16591 | 1/20 | 0.48 |
| ▸ | LTK | P29376 | 1/20 | 0.48 |
| ▸ | CDK8 | P49336 | 1/20 | 0.48 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.48 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29369547 | 0.80 | GAA (0.59) | ACVR1LRRK2PDGFRAFERLTK | |
| SCHEMBL2676730 | 0.80 | GAA (0.59) | ACVR1LRRK2PDGFRAFERLTK | |
| SCHEMBL76607 | 0.80 | — | — | |
| SCHEMBL624418 | 0.80 | GAA (0.59) | ACVR1LRRK2PDGFRAFERLTK | |
| Formaldehyde SCHEMBL1144590 | 0.78 | — | — | |
| Fluoride SCHEMBL6264312 | 0.77 | — | — | |
| Water SCHEMBL3526962 | 0.77 | — | — | |
| SCHEMBL7171963 | 0.77 | GAA (0.56) | ACVR1LRRK2PDGFRAFERLTK | |
| SCHEMBL28900384 | 0.77 | ACVR1 (0.48) | ACVR1LRRK2PDGFRAFERLTK | |
| Naphthalene SCHEMBL5071443 | 0.71 | ALOX12 (0.57) | ACVR1LRRK2PDGFRAFERLTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4923504-A | 2-(2-Imidazolin-2-yl)pyridines and quinolines, and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1990-05-08 | — | — | US | disclosed |
| US-4798619-A | 2-(2-imidazolin-2-yl)-pyridines and quinolines and use of said compounds as herbicidal agents | AMERICAN CYANAMID CO. (US) | 1989-01-17 | — | — | US | disclosed |
| US-4638068-A | 2-(2-imidazolin-2-yl)-pyridines and quinolines, process and intermediates for the preparation thereof, and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1987-01-20 | — | — | US | disclosed |
| EP-0041623-B1 | SUBSTITUTED IMIDAZOLINYL NICOTINE ACIDS, ESTERS AND SALTS AND USE THEREOF AS HERBICIDAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1985-08-28 | — | — | EP | disclosed |
| EP-0041624-B1 | METHOD TO BENEFICIALLY INFLUENCE & ALTER THE DEVELOPMENT & LIFE CYCLE OF AGRONOMIC AND HORTICULTURAL CROPS WITH CERTAIN IMIDAZOLINYL NICOTINIC ACIDS AND DERIVATIVES THEREOF | AMERICAN CYANAMID COMPANY (US) | 1984-02-01 | — | — | EP | disclosed |
| EP-0041623-A2 | Substituted imidazolinyl nicotine acids, esters and salts and use thereof as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1981-12-16 | — | — | EP | disclosed |
| EP-0041624-A2 | Method to beneficially influence & alter the development & life cycle of agronomic and horticultural crops with certain imidazolinyl nicotinic acids and derivatives thereof | AMERICAN CYANAMID COMPANY (US) | 1981-12-16 | — | — | EP | disclosed |