Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10431978 | 0.77 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3TSHRCHRNB2 | |
| SCHEMBL29277743 | 0.77 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3TSHRCHRNB2 | |
| SCHEMBL10663216 | 0.77 | HTR2A (0.37) | SLC6A2SLC6A4SLC6A3TSHRCYP1A2 | |
| SCHEMBL11100946 | 0.77 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3TSHRCHRNB2 | |
| SCHEMBL10666352 | 0.77 | HTR2A (0.37) | SLC6A2SLC6A4SLC6A3TSHRCYP1A2 | |
| SCHEMBL29277741 | 0.77 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3TSHRCHRNB2 | |
| SCHEMBL10659974 | 0.76 | HTR2A (0.36) | SLC6A2SLC6A4SLC6A3TSHRCYP1A2 | |
| SCHEMBL10663765 | 0.76 | TSHR (0.39) | SLC6A2SLC6A4SLC6A3TSHRCHRNB2 | |
| SCHEMBL6972092 | 0.76 | L3MBTL1 (0.42) | SLC6A2SLC6A4SLC6A3TSHRMEN1 | |
| SCHEMBL6691876 | 0.74 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3TSHRCHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4973598-A | Substituted imidazolinones and imidazolinethiones | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-27 | — | — | US | disclosed |