Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HRH1 | P35367 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SCN1A | P35498 | 3/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10663216 | 0.79 | HTR2A (0.37) | LMNAHTTHTR2AHRH1SMN1; SMN2 | |
| SCHEMBL10666352 | 0.79 | HTR2A (0.37) | LMNAHTTHTR2AHRH1SMN1; SMN2 | |
| SCHEMBL10659974 | 0.77 | HTR2A (0.36) | LMNAHTTHTR2AHRH1SMN1; SMN2 | |
| SCHEMBL10663765 | 0.77 | TSHR (0.39) | LMNAHTTHTR2AHRH1SMN1; SMN2 | |
| SCHEMBL27191 | 0.76 | ACHE (0.47) | L3MBTL1LMNAPOLBHTTHTR2A | |
| SCHEMBL3992907 | 0.76 | SCN1A (0.55) | L3MBTL1LMNAPOLBHTTHTR2A | |
| SCHEMBL10472525 | 0.76 | SLC6A2 (0.47) | HTTSMN1; SMN2MEN1KMT2ACYP1A2 | |
| SCHEMBL21243279 | 0.76 | HTT (0.42) | L3MBTL1LMNAPOLBHTTHTR2A | |
| SCHEMBL20012560 | 0.74 | L3MBTL1 (0.44) | L3MBTL1LMNAPOLBHTTHTR2A | |
| SCHEMBL11982736 | 0.74 | L3MBTL1 (0.44) | L3MBTL1LMNAPOLBHTTHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-4728646-A | ANTITHROMBOTICS | DR. KARL THOMAE GMBH (DE) | 1988-03-01 | — | — | US | disclosed |
| US-4518596-A | Antithrombotic use of 2-(perhydro-1,4-diazino)-pyrimido (5,4,D)-pyrimidines | DR. KARL THOMAE GMBH (DE) | 1985-05-21 | — | — | US | disclosed |