Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.48 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31490450 | 1.00 | IRAK4 (0.48) | IRAK4NISCHACHEALDH1A1TSHR | |
| SCHEMBL28883167 | 0.98 | IRAK4 (0.47) | IRAK4NISCHACHEALDH1A1TSHR | |
| Ammonia Solution, Strong SCHEMBL5891986 | 0.98 | IRAK4 (0.47) | IRAK4NISCHACHEALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL4624005 | 0.98 | IRAK4 (0.47) | IRAK4NISCHACHEALDH1A1TSHR | |
| SCHEMBL28700751 | 0.91 | IRAK4 (0.43) | IRAK4NISCHACHEALDH1A1TSHR | |
| Formic Acid SCHEMBL28111659 | 0.88 | IRAK4 (0.49) | IRAK4NISCHACHEALDH1A1TSHR | |
| SCHEMBL1592873 | 0.85 | NISCH (0.47) | NISCHACHETSHRKMT2AMEN1 | |
| SCHEMBL29591819 | 0.84 | ALDH1A1 (0.57) | IRAK4NISCHACHEALDH1A1KMT2A | |
| SCHEMBL2069775 | 0.84 | ALDH1A1 (0.57) | IRAK4NISCHACHEALDH1A1KMT2A | |
| SCHEMBL28911420 | 0.82 | TSHR (0.46) | NISCHACHEALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 326 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107840902-B | Preparation method of reinforcing plasticizer for nitrile rubber | 中国石油天然气股份有限公司 | 2020-09-04 | — | — | CN | claimed |
| CN-107841007-B | Preparation method of easily processed reinforced nitrile rubber | 中国石油天然气股份有限公司 | 2020-09-04 | — | — | CN | claimed |
| CN-107540896-B | Preparation method of easily-processed flame-retardant nitrile rubber | 中国石油天然气股份有限公司 | 2020-09-04 | — | — | CN | claimed |
| CN-107540893-B | Easily-processed flame-retardant nitrile rubber and preparation method thereof | 中国石油天然气股份有限公司 | 2020-09-04 | — | — | CN | claimed |
| CN-107841009-B | Easily-processed anti-aging styrene butadiene rubber and preparation method thereof | 中国石油天然气股份有限公司 | 2020-09-04 | — | — | CN | claimed |
| CN-107841010-B | Preparation method of easy-to-process reinforced styrene butadiene rubber | 中国石油天然气股份有限公司 | 2020-09-04 | — | — | CN | claimed |
| CN-107841004-B | Preparation method of easily-processed anti-aging nitrile rubber | 中国石油天然气股份有限公司 | 2020-09-04 | — | — | CN | claimed |
| CN-107841006-B | Easily-processed anti-aging nitrile rubber and preparation method thereof | 中国石油天然气股份有限公司 | 2020-08-07 | — | — | CN | claimed |
| CN-107841011-B | Preparation method of easily-processed anti-aging styrene butadiene rubber | 中国石油天然气股份有限公司 | 2020-08-07 | — | — | CN | claimed |
| CN-107841008-B | Easily-processed reinforced styrene butadiene rubber and preparation method thereof | 中国石油天然气股份有限公司 | 2020-08-07 | — | — | CN | claimed |
| CN-107841005-B | Easily-processed reinforced nitrile rubber and preparation method thereof | 中国石油天然气股份有限公司 | 2020-08-07 | — | — | CN | claimed |
| CN-107840903-B | Preparation method of reinforced softener for styrene butadiene rubber | 中国石油天然气股份有限公司 | 2020-08-07 | — | — | CN | claimed |
| CN-107540765-B | Preparation method of flame-retardant plasticizer for nitrile rubber | 中国石油天然气股份有限公司 | 2020-06-09 | — | — | CN | claimed |
| CN-104430357-A | Bactericide composition containing coumoxystrobin with synergistic effect | JILIN BADA PESTICIDE CO LTD | 2015-03-25 | — | — | CN | claimed |
| US-8088797-B2 | Substituted N-(4-cyano-1H-pyrazol-3-yl)methylamine derivatives, preparation thereof and therapeutic use thereof | SANOFI-AVENTIS (FR) | 2012-01-03 | — | — | US | claimed |
| US-20100041709-A1 | SUBSTITUTED N-(4-CYANO-1H-PYRAZOL-3-YL)METHYLAMINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-02-18 | — | — | US | claimed |
| EP-0365328-B1 | Pyridine derivatives | ZENECA LTD (GB) | 1996-04-03 | — | — | EP | claimed |
| US-5053415-A | Antiischemic, antiinflammatory, antiarthritic agents, cardiovascular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-01 | — | — | US | claimed |
| EP-0365328-A2 | Pyridine derivatives | ZENECA LIMITED (GB) | 1990-04-25 | — | — | EP | claimed |
| EP-0069906-A2 | Water-based aerosol formulations | BAYER AG (DE) | 1983-01-19 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041709-A1 | SUBSTITUTED N-(4-CYANO-1H-PYRAZOL-3-YL)METHYLAMINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | PRMT3, PRMT5, PRMT1 | IRAK4 898/4885NISCH 1583/4885ACHE 320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.