Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14408833 | 0.86 | MEN1 (0.48) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL20618157 | 0.84 | MEN1 (0.49) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL17338584 | 0.79 | MAPT (0.46) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL2570325 | 0.78 | ALDH1A1 (0.52) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL20614801 | 0.76 | GAA (0.40) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL18858382 | 0.76 | ALDH1A1 (0.59) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL22363252 | 0.76 | AVPR2 (0.48) | — | |
| SCHEMBL12156542 | 0.75 | CYP2C19 (0.47) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL947365 | 0.75 | ALDH1A1 (0.55) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL29683518 | 0.75 | ALDH1A1 (0.55) | MEN1KMT2AL3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4952573-A | FOR CONTROLLING TISSUE STABILITY DURING EYE SURGERY; ANTISWELLING AGENT | LABORATOIRS ALCON S.A. (FR) | 1990-08-28 | — | — | US | disclosed |