Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL59093 | 0.88 | SMN1; SMN2 (0.61) | MEN1KMT2AHTTALDH1A1MAPT | |
| SCHEMBL8770096 | 0.87 | MAPT (0.64) | MEN1KMT2AALDH1A1MAPTTP53 | |
| SCHEMBL11479190 | 0.86 | ALDH1A1 (0.68) | MEN1KMT2AHTTALDH1A1MAPT | |
| SCHEMBL441802 | 0.80 | MEN1 (0.83) | MEN1KMT2AHTTALDH1A1MAPT | |
| SCHEMBL12679042 | 0.80 | MEN1 (0.83) | MEN1KMT2AHTTALDH1A1MAPT | |
| SCHEMBL12125125 | 0.78 | MAPT (0.67) | MEN1KMT2AHTTALDH1A1MAPT | |
| SCHEMBL14358667 | 0.78 | MAPT (0.60) | MEN1KMT2AHTTALDH1A1MAPT | |
| SCHEMBL14358669 | 0.78 | MAPT (0.60) | MEN1KMT2AHTTALDH1A1MAPT | |
| SCHEMBL8817969 | 0.78 | MAPT (0.67) | MEN1KMT2AHTTALDH1A1MAPT | |
| SCHEMBL10361939 | 0.77 | RXFP1 (0.59) | MEN1KMT2AALDH1A1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4898941-A | Process for preparing diphenylalkene derivatives | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1990-02-06 | — | — | US | disclosed |
| EP-0257591-A2 | Process for preparing diphenylalkene derivatives | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |