Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | PPOX | P50336 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 8/20 | 0.35 |
| ▸ | PPARG | P37231 | 6/20 | 0.35 |
| ▸ | PPARD | Q03181 | 6/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10474194 | 0.88 | TDP1 (0.37) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10473691 | 0.87 | MEN1 (0.37) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10474342 | 0.86 | MEN1 (0.36) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10472077 | 0.85 | MEN1 (0.36) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10471923 | 0.85 | TDP1 (0.36) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL8357453 | 0.85 | MERTK (0.43) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10472692 | 0.85 | TDP1 (0.41) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10472096 | 0.85 | MEN1 (0.41) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10474196 | 0.84 | TDP1 (0.40) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10474161 | 0.83 | TDP1 (0.45) | MEN1KMT2ATDP1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4964895-A | Substituted 4-(4-nitrophenoxy) pyrazoles and their use as herbicides | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | disclosed |