Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | PPOX | P50336 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10472555 | 0.92 | TDP1 (0.38) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10474160 | 0.92 | TDP1 (0.38) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10473577 | 0.92 | TDP1 (0.38) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10472692 | 0.92 | TDP1 (0.41) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10472090 | 0.91 | RAB9A (0.37) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10471772 | 0.90 | TDP1 (0.36) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL8351753 | 0.89 | KMT2A (0.36) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10474052 | 0.89 | MEN1 (0.39) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10474247 | 0.88 | TDP1 (0.36) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL9442572 | 0.87 | ALDH1A1 (0.36) | TDP1MEN1TTRPPOXKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4964895-A | Substituted 4-(4-nitrophenoxy) pyrazoles and their use as herbicides | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | disclosed |