Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | PPOX | P50336 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10473691 | 0.99 | MEN1 (0.37) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL10474194 | 0.95 | TDP1 (0.37) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL10471923 | 0.86 | TDP1 (0.36) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL10473602 | 0.86 | MEN1 (0.41) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL10472209 | 0.83 | GAA (0.36) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL10472096 | 0.81 | MEN1 (0.41) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL10472071 | 0.81 | MAPT (0.41) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL9597853 | 0.80 | TDP1 (0.40) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL9442572 | 0.80 | ALDH1A1 (0.36) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL10472077 | 0.80 | MEN1 (0.36) | MEN1TTRPPOXKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4964895-A | Substituted 4-(4-nitrophenoxy) pyrazoles and their use as herbicides | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | disclosed |