Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 7/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10472693 | 0.99 | BCHE (0.35) | NAAABCHEACHEMAOBMAOA | |
| SCHEMBL10473938 | 0.86 | FKBP1A (0.39) | FKBP1A | |
| SCHEMBL10473300 | 0.84 | PDE4A (0.35) | FKBP1AS1PR1 | |
| SCHEMBL10474087 | 0.84 | PDE4A (0.35) | FKBP1AS1PR1 | |
| SCHEMBL10473627 | 0.84 | PDE4A (0.35) | FKBP1AS1PR1 | |
| SCHEMBL10473298 | 0.84 | PDE4A (0.35) | FKBP1AS1PR1 | |
| SCHEMBL10472786 | 0.79 | HPGD (0.37) | NAAABCHEACHEFFAR1FKBP1A | |
| SCHEMBL10474094 | 0.78 | ACHE (0.41) | NAAABCHEACHEMAOBMAOA | |
| SCHEMBL11191930 | 0.78 | MAOB (0.38) | BCHEACHEMAOBMAOAFFAR1 | |
| SCHEMBL11175220 | 0.78 | MAOB (0.38) | BCHEACHEMAOBMAOAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920221-A | CENTRAL NERVOUS SYSTEM ACTIVE AGENTS | PFIZER INC. (US) | 1990-04-24 | — | — | US | disclosed |
| US-4642373-A | Substituted dodecahydrotripheylenes, and decahydropyrrolo[1,2-f]phenanthridines as CNS agents | PFIZER INC. (US) | 1987-02-10 | — | — | US | disclosed |
| US-4473704-A | ANALGESICS, ANTIEMETICS | PFIZER INC. (US) | 1984-09-25 | — | — | US | disclosed |