Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | MIF | P14174 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1162464 | 0.93 | CYP2C19 (0.35) | CYP2C19ALOX15KDM4EMAPTCYP3A4 | |
| Formic Acid SCHEMBL1162475 | 0.93 | CYP2D6 (0.35) | CYP2C19ALOX15KDM4EMAPTCYP3A4 | |
| SCHEMBL28429021 | 0.91 | CYP2C19 (0.34) | CYP2C19ALOX15KDM4EMAPTCYP3A4 | |
| Phosphonic Acid SCHEMBL1162520 | 0.91 | CYP2C19 (0.34) | CYP2C19ALOX15KDM4EMAPTCYP3A4 | |
| SCHEMBL5800479 | 0.86 | PGK1 (0.31) | — | |
| SCHEMBL4443347 | 0.80 | MIF (0.52) | CYP2C19ALOX15KDM4EMAPTCYP3A4 | |
| SCHEMBL29812875 | 0.80 | CYP2D6 (0.35) | MIFLMNATSHRCYP2D6SRC | |
| SCHEMBL6889278 | 0.80 | MIF (0.34) | CYP2C19ALOX15KDM4EMAPTCYP3A4 | |
| SCHEMBL3519342 | 0.77 | MIF (0.36) | MIFMEN1KMT2A | |
| SCHEMBL3258485 | 0.77 | KDM4E (0.40) | CYP2C19ALOX15KDM4EMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 250 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630784-B1 | PREPARATION OF ISOCYANATOSILANES | MOMENTIVE PERFORMANCE MAT INC (US) | 2021-07-07 | — | — | EP | claimed |
| EP-3630784-A1 | PREPARATION OF ISOCYANATOSILANES | Momentive Performance Materials Inc. (US) | 2020-04-08 | — | — | EP | claimed |
| CN-110691786-A | Preparation of isocyanatosilanes | 莫门蒂夫性能材料股份有限公司 | 2020-01-14 | — | — | CN | claimed |
| US-10266554-B2 | Preparation of isocyanatosilanes | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2019-04-23 | — | — | US | claimed |
| WO-2018222486-A1 | PREPARATION OF ISOCYANATOSILANES | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2018-12-06 | — | — | WO | claimed |
| US-20180346493-A1 | PREPARATION OF ISOCYANATOSILANES | MOMENTIVE PERFORMANCE MATERIALS INC. | 2018-12-06 | — | — | US | claimed |
| CN-103554168-B | Epoxy radicals silicone hydride, its preparation method and the curable compositions comprising it | 莫门蒂夫性能材料股份有限公司 | 2017-07-18 | — | — | CN | claimed |
| US-8889800-B2 | Terminal-modified difunctional sulfur-containing polymers, compositions thereof and methods of use | PRC-DESOTO INTERNATIONAL, INC. (US) | 2014-11-18 | — | — | US | claimed |
| US-20140255609-A1 | TERMINAL-MODIFIED DIFUNCTIONAL SULFUR-CONTAINING POLYMERS, COMPOSITIONS THEREOF AND METHODS OF USE | PRC-DESOTO INTERNATIONAL, INC. | 2014-09-11 | — | — | US | claimed |
| EP-1534759-B1 | MACROMER FORMING CATALYSTS | JOHNSON & JOHNSON VISION CARE (US) | 2009-09-09 | — | — | EP | claimed |
| EP-0907668-B1 | AMPHIPHILIC, SEGMENTED COPOLYMER OF CONTROLLED MORPHOLOGY AND OPHTHALMIC DEVICES INCLUDING CONTACT LENSES MADE THEREFROM | NOVARTIS AG (CH) | 2001-09-19 | — | — | EP | claimed |
| US-6043328-A | MOLDINGS, CONTACT LENSES, CORNEAL IMPLANTS OR BIOMEDICAL ARTICLES, | NOVARTIS AG (CH) | 2000-03-28 | — | — | US | claimed |
| EP-0826158-B1 | POLYSILOXANE-POLYOL MACROMERS, THEIR PREPARATION AND THEIR USE | NOVARTIS AG (CH) | 1999-09-15 | — | — | EP | claimed |
| EP-0826158-A1 | POLYSILOXANE-POLYOL MACROMERS, THEIR PREPARATION AND THEIR USE | Novartis AG (CH) | 1998-03-04 | — | — | EP | claimed |
| WO-1996036890-A1 | POLYSILOXANE-POLYOL MACROMERS, THEIR PREPARATION AND THEIR USE | NOVARTIS AG (CH) | 1996-11-21 | — | — | WO | claimed |
| EP-0415123-B1 | 1-Phenylalkyl-3-phenylurea derivatives | MITSUBISHI CHEM IND (JP) | 1994-12-07 | — | — | EP | claimed |
| EP-0439059-B1 | 1-Phenylalkyl-3-phenylurea derivative | MITSUBISHI CHEM IND (JP) | 1994-08-24 | — | — | EP | claimed |
| EP-0439059-A2 | 1-Phenylalkyl-3-phenylurea derivative | Mitsubishi Chemical Corporation (JP) | 1991-07-31 | — | — | EP | claimed |
| EP-0415123-A2 | 1-Phenylalkyl-3-phenylurea derivatives | Mitsubishi Chemical Corporation (JP) | 1991-03-06 | — | — | EP | claimed |
| US-4430326-A | Method of diminishing glucose levels resulting from endogenous glucagon | UNIVERSITY PATENTS, INC. (US) | 1984-02-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180346493-A1 | PREPARATION OF ISOCYANATOSILANES | IDH3A, IDH2, IDH1 | CYP2C19 1757/4885ALOX15 3458/4885KDM4E 1663/4885 |
| US-10266554-B2 | Preparation of isocyanatosilanes | IDH3A, IDH2, IDH1 | CYP2C19 1757/4885ALOX15 3458/4885KDM4E 1663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.