SCHEMBL28429021

SCHEMBL28429021

C=CC(N=C=O)c1ccccc1.O=[SH](=O)O

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.34
LMNA P02545 1/20 0.32
ALOX15 P16050 3/20 0.31
KDM4E B2RXH2 2/20 0.31
CYP3A4 P08684 2/20 0.31
MAPT P10636 2/20 0.31
TSHR P16473 1/20 0.31
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
HPGD P15428 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CYP2D6 P10635 1/20 0.31
SRC P12931 1/20 0.31
MIF P14174 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1047388 0.91 CYP2C19 (0.35) CYP2C19LMNAALOX15KDM4ECYP3A4
SCHEMBL1162464 0.88 CYP2C19 (0.35) CYP2C19LMNAALOX15KDM4ECYP3A4
Formic Acid SCHEMBL1162475 0.88 CYP2D6 (0.35) CYP2C19LMNAALOX15KDM4ECYP3A4
Phosphonic Acid SCHEMBL1162520 0.87 CYP2C19 (0.34) CYP2C19LMNAALOX15KDM4ECYP3A4
SCHEMBL5800479 0.79 PGK1 (0.31)
SCHEMBL6889278 0.73 MIF (0.34) CYP2C19ALOX15KDM4ECYP3A4MAPT
SCHEMBL4443347 0.73 MIF (0.52) CYP2C19ALOX15KDM4ECYP3A4MAPT
SCHEMBL29812875 0.73 CYP2D6 (0.35) LMNATSHRCYP2D6SRCMIF
SCHEMBL1563451 0.72 TRPA1 (0.36) LMNAHPGDKMT2ACYP2D6SRC
SCHEMBL3519342 0.70 MIF (0.36) MEN1KMT2AMIF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111405934-B Method for isolating, separating, purifying or detecting acidic polar molecules 沃特世科技公司 2022-04-26 CN disclosed
CN-111405934-A High purity chromatographic materials comprising ionizable modifiers for retention of acidic analytes 沃特世科技公司 2020-07-10 CN disclosed