Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18883851 | 0.98 | EPHX1 (0.45) | ALDH1A1NPSR1EPHX1HTTKCNH3 | |
| SCHEMBL18883838 | 0.82 | MAPT (0.44) | ALDH1A1HTTMAPTGAACYP2C9 | |
| SCHEMBL18883842 | 0.81 | KCNH3 (0.43) | ALDH1A1NPSR1HTTKCNH3MAPT | |
| SCHEMBL18891021 | 0.77 | MEN1 (0.43) | HTTMEN1KMT2A | |
| SCHEMBL18883854 | 0.75 | THRB (0.36) | ALDH1A1HTTMAPTCYP2C9GMNN | |
| SCHEMBL18883960 | 0.75 | THRB (0.36) | ALDH1A1HTTMAPTCYP2C9GMNN | |
| SCHEMBL18883839 | 0.75 | SMN1; SMN2 (0.42) | ALDH1A1HTTMAPTGAAMEN1 | |
| SCHEMBL31326852 | 0.75 | MAPT (0.48) | ALDH1A1NPSR1EPHX1HTTMAPT | |
| SCHEMBL18883852 | 0.75 | MAPT (0.55) | ALDH1A1HTTMAPTGAAHSD17B10 | |
| SCHEMBL31326854 | 0.75 | MAPT (0.48) | ALDH1A1NPSR1EPHX1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4923504-A | 2-(2-Imidazolin-2-yl)pyridines and quinolines, and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1990-05-08 | — | — | US | disclosed |
| US-4798619-A | 2-(2-imidazolin-2-yl)-pyridines and quinolines and use of said compounds as herbicidal agents | AMERICAN CYANAMID CO. (US) | 1989-01-17 | — | — | US | disclosed |
| US-4638068-A | 2-(2-imidazolin-2-yl)-pyridines and quinolines, process and intermediates for the preparation thereof, and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1987-01-20 | — | — | US | disclosed |
| EP-0041623-B1 | SUBSTITUTED IMIDAZOLINYL NICOTINE ACIDS, ESTERS AND SALTS AND USE THEREOF AS HERBICIDAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1985-08-28 | — | — | EP | disclosed |
| EP-0041623-A2 | Substituted imidazolinyl nicotine acids, esters and salts and use thereof as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1981-12-16 | — | — | EP | disclosed |
| EP-0041624-A2 | Method to beneficially influence & alter the development & life cycle of agronomic and horticultural crops with certain imidazolinyl nicotinic acids and derivatives thereof | AMERICAN CYANAMID COMPANY (US) | 1981-12-16 | — | — | EP | disclosed |