Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | PPOX | P50336 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.32 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10473397 | 0.89 | MEN1 (0.34) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10474933 | 0.89 | TDP1 (0.35) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10474934 | 0.89 | TDP1 (0.35) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10474774 | 0.88 | MEN1 (0.35) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10474196 | 0.88 | TDP1 (0.40) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10474160 | 0.87 | TDP1 (0.38) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10472555 | 0.87 | TDP1 (0.38) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10473577 | 0.87 | TDP1 (0.38) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL8357453 | 0.87 | MERTK (0.43) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10472692 | 0.87 | TDP1 (0.41) | TDP1MEN1TTRPPOXKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4964895-A | Substituted 4-(4-nitrophenoxy) pyrazoles and their use as herbicides | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | disclosed |