Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | PPOX | P50336 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10474196 | 0.92 | TDP1 (0.40) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10473577 | 0.91 | TDP1 (0.38) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10471772 | 0.89 | TDP1 (0.36) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10472555 | 0.89 | TDP1 (0.38) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL8351753 | 0.89 | KMT2A (0.36) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10472692 | 0.87 | TDP1 (0.41) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10474247 | 0.87 | TDP1 (0.36) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL9442572 | 0.86 | ALDH1A1 (0.36) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10474933 | 0.85 | TDP1 (0.35) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10474934 | 0.85 | TDP1 (0.35) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4964895-A | Substituted 4-(4-nitrophenoxy) pyrazoles and their use as herbicides | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | disclosed |