Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3816097 | 0.87 | TDP1 (0.44) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL24252816 | 0.85 | MEN1 (0.49) | MEN1KMT2AMAPTS1PR4LMNA | |
| SCHEMBL30451233 | 0.85 | MEN1 (0.49) | MEN1KMT2AMAPTS1PR4LMNA | |
| SCHEMBL1568424 | 0.85 | DGAT1 (0.43) | MEN1KMT2AMAPTS1PR4LMNA | |
| SCHEMBL28530497 | 0.83 | MEN1 (0.44) | MEN1KMT2AMAPTS1PR4LMNA | |
| SCHEMBL10475593 | 0.80 | CASP1 (0.42) | — | |
| SCHEMBL8286314 | 0.76 | MEN1 (0.39) | MEN1KMT2AMAPTS1PR4LMNA | |
| SCHEMBL3846563 | 0.76 | CYP4F2 (0.55) | LMNAALDH1A1TSHRCYP4F2CYP4A11 | |
| SCHEMBL3411086 | 0.76 | MEN1 (0.47) | MEN1KMT2AMAPTS1PR4LMNA | |
| SCHEMBL3411087 | 0.76 | MEN1 (0.47) | MEN1KMT2AMAPTS1PR4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4959363-A | HERPES VIRUS | STERLING DRUG INC. (US) | 1990-09-25 | — | — | US | disclosed |