Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 0.52 |
| ▸ | CDK1 | P06493 | 4/20 | 0.52 |
| ▸ | PRKACA | P17612 | 4/20 | 0.52 |
| ▸ | CDK2 | P24941 | 4/20 | 0.52 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.52 |
| ▸ | GSK3A | P49840 | 4/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.52 |
| ▸ | CDC42BPA | Q5VT25 | 4/20 | 0.52 |
| ▸ | MARK2 | Q7KZI7 | 3/20 | 0.52 |
| ▸ | DYRK3 | O43781 | 3/20 | 0.52 |
| ▸ | RPS6KA5 | O75582 | 3/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.52 |
| ▸ | CLK2 | P49760 | 3/20 | 0.52 |
| ▸ | GSK3B | P49841 | 3/20 | 0.52 |
| ▸ | IRAK1 | P51617 | 3/20 | 0.52 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.52 |
| ▸ | PRKX | P51817 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10475303 | 0.91 | ROCK2 (0.63) | ROCK2CDK1PRKACACDK2CSNK1D | |
| SCHEMBL10474604 | 0.91 | ROCK2 (0.52) | ROCK2CDK1PRKACACDK2CSNK1D | |
| SCHEMBL11655148 | 0.90 | CAPN1 (0.50) | ROCK2CDK1PRKACACDK2CSNK1D | |
| Rosoxacin SCHEMBL135645 | 0.87 | CAPN1 (0.61) | ROCK2CDK1PRKACACDK2CSNK1D | |
| Rosoxacin SCHEMBL29361483 | 0.87 | CAPN1 (0.61) | ROCK2CDK1PRKACACDK2CSNK1D | |
| SCHEMBL10474600 | 0.86 | CAPN1 (0.62) | ROCK2CDK1PRKACACDK2CSNK1D | |
| SCHEMBL11652572 | 0.81 | ROCK2 (0.48) | ROCK2CDK1PRKACACDK2CSNK1D | |
| SCHEMBL5195646 | 0.80 | CAPN1 (0.47) | ROCK2CDK1PRKACACDK2CSNK1D | |
| SCHEMBL10474587 | 0.79 | CNR1 (0.54) | ROCK2CDK1PRKACACDK2CSNK1D | |
| SCHEMBL10475298 | 0.78 | CAPN1 (0.59) | ROCK2CDK1PRKACACDK2CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4959363-A | HERPES VIRUS | STERLING DRUG INC. (US) | 1990-09-25 | — | — | US | disclosed |