SCHEMBL1047441

SCHEMBL1047441

CCCC(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.48
TAAR1 Q96RJ0 4/20 0.48
SLC6A2 P23975 2/20 0.48
MAOA P21397 1/20 0.48
SLC6A4 P31645 1/20 0.48
SLC6A3 Q01959 1/20 0.48
CYP2A6 P11509 1/20 0.48
ADORA2A P29274 1/20 0.48
ADORA1 P30542 1/20 0.48
EPHX1 P07099 1/20 0.46
TP53 P04637 1/20 0.46
TRPA1 O75762 1/20 0.45
SLC18A2 Q05940 1/20 0.45
CYP2D6 P10635 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9543263 0.95 SIGMAR1 (0.48) SIGMAR1TAAR1SLC6A2MAOASLC6A4
SCHEMBL7252245 0.92 TRPA1 (0.57) SIGMAR1TAAR1SLC6A2MAOASLC6A4
SCHEMBL15562967 0.91 SIGMAR1 (0.49) SIGMAR1TAAR1SLC6A2MAOASLC6A4
SCHEMBL27653268 0.89 SIGMAR1 (0.47) SIGMAR1TAAR1SLC6A2MAOASLC6A4
SCHEMBL9846054 0.87 SIGMAR1 (0.47) SIGMAR1TAAR1SLC6A2MAOASLC6A4
SCHEMBL2846535 0.87 SIGMAR1 (0.47) SIGMAR1TAAR1SLC6A2MAOASLC6A4
SCHEMBL28905176 0.87 SIGMAR1 (0.43) SIGMAR1TAAR1SLC6A2MAOASLC6A4
SCHEMBL14402660 0.87 TRPA1 (0.52) SIGMAR1TAAR1SLC6A2MAOASLC6A4
SCHEMBL15562664 0.87 CSNK1E (0.47) SIGMAR1TAAR1SLC6A2MAOASLC6A4
SCHEMBL28258282 0.87 SIGMAR1 (0.43) SIGMAR1TAAR1SLC6A2MAOASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036599-A Dibenzylbutane lignan LCA analogue, and preparation method and application thereof 浙江中医药大学 2026-05-15 CN claimed
CN-119876062-A Polypeptide for catalyzing lignan cyclization, encoding gene, preparation method and application 中国医学科学院药用植物研究所 2025-04-25 CN claimed
CN-119859620-A Polypeptide for catalyzing hydroxylation of lignans, encoding gene, preparation method and application 中国医学科学院药用植物研究所 2025-04-22 CN claimed
CN-116444461-B Dibenzylbutane lignan LCA derivative and application thereof 中国人民解放军海军军医大学 2024-12-24 CN claimed
CN-117247331-A Dibenzylbutane type lignan analogue and application thereof 中国人民解放军海军军医大学 2023-12-19 CN claimed
CN-116606832-A Dibenzylbutane lignan oxymethyl transferase and application thereof 中国医学科学院药用植物研究所 2023-08-18 CN claimed
CN-116478949-A Lignan oxymethyl transferase and use thereof 中国医学科学院药用植物研究所 2023-07-25 CN claimed
CN-116444461-A Dibenzylbutane lignan LCA derivative and application thereof 中国人民解放军海军军医大学 2023-07-18 CN claimed
WO-2009082794-A1 PLANT EXTRACTS WITH ANTIMICROBIAL NEOLIGNANS, THEIR COMPOSITION AND PROCESS FOR EXTRACT PRODUCTION INSTITUTO NACIONAL DE PESQUISA DA AMAZÔNIA - INPA (BR) 2009-07-09 WO claimed
US-6967229-B2 Carbon-carbon initiators for use in golf balls ACUSHNET COMPANY (US) 2005-11-22 US claimed
US-20050009992-A1 Carbon-carbon initiators for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US claimed
CN-122036599-A Dibenzylbutane lignan LCA analogue, and preparation method and application thereof 浙江中医药大学 2026-05-15 CN disclosed
CN-122036599-A Dibenzylbutane lignan LCA analogue, and preparation method and application thereof 浙江中医药大学 2026-05-15 CN disclosed
CN-122036599-A Dibenzylbutane lignan LCA analogue, and preparation method and application thereof 浙江中医药大学 2026-05-15 CN disclosed
EP-4606437-A1 COSMETIC COMPOSITIONS TO INHIBIT THE ACTIVITY OF KLF4, TO REDUCE SKIN, HAIR, MUCOUS MEMBRANES AGING LABORATOIRE NATIVE (FR) 2025-08-27 EP disclosed
US-5705618-A Process for extracting lignans from flaxseed AGRICULTURE AND AGRI-FOOD CANADA (CA) 1998-01-06 US disclosed
US-5663440-A Diamino compounds and methods for preparing them CHISSO CORPORATION (JP) 1997-09-02 US disclosed
WO-1996030468-A2 PROCESS FOR EXTRACTING AND PURIFYING LIGNANS AND CINNAMIC ACID DERIVATIVES FROM FLAXSEED HER MAJESTY IN RIGHT OF CANADA, represented by THEMINISTER OF AGRICULTURE AND AGRI-FOOD CANADA (CA) 1996-10-03 WO disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed
EP-0708077-A1 Diamino compounds and methods for preparing them CHISSO CORPORATION (JP) 1996-04-24 EP disclosed