Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687546 | 0.89 | HPGD (0.51) | MAPTTP53RXFP1HPGDALDH1A1 | |
| SCHEMBL9687582 | 0.85 | HPGD (0.50) | MAPTTP53TSHRHSD17B10RXFP1 | |
| SCHEMBL9688594 | 0.84 | TP53 (0.45) | MTNR1AMTNR1BMAPTTP53RXFP1 | |
| SCHEMBL9688674 | 0.84 | HRH3 (0.47) | MAPTTP53GAAHDAC1HDAC6 | |
| SCHEMBL9688808 | 0.83 | ALDH1A1 (0.42) | MAPTTP53HSD17B10RXFP1HPGD | |
| Hydrochloric Acid SCHEMBL9688836 | 0.82 | TP53 (0.43) | MTNR1AMTNR1BMAPTTP53RXFP1 | |
| Hydrochloric Acid SCHEMBL9689421 | 0.82 | HRH3 (0.48) | GAAHDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL9688700 | 0.81 | ALDH1A1 (0.41) | MAPTTP53HSD17B10RXFP1HPGD | |
| SCHEMBL9687685 | 0.80 | HDAC1 (0.45) | MAPTTP53HPGDALDH1A1HDAC1 | |
| SCHEMBL9689143 | 0.79 | ESRRG (0.42) | MAPTTP53TSHRRXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968699-A | CENTRAL NERVOUS SYSTEM; ANTIISCHEMIC AND ANTIHYPOXIC AGENTS; ACTIVE AGAINST CEREBRAL OXYGEN DEFICIENCY | BEECHAM-WUELFING GMBH & CO. (DE) | 1990-11-06 | — | — | US | disclosed |