Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 9/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10475063 | 0.81 | GAA (0.51) | GAAKMT2ALMNAPKMPOLB | |
| SCHEMBL10475129 | 0.81 | GAA (0.74) | GAAKMT2ALMNAPKMPOLB | |
| SCHEMBL13806891 | 0.79 | GAA (0.68) | GAAKMT2ALMNAPKMPOLB | |
| SCHEMBL9901661 | 0.76 | MAPK1 (0.45) | GAAKMT2ALMNAPKMPOLB | |
| Hydrochloric Acid SCHEMBL28436907 | 0.75 | GAA (0.46) | GAAKMT2ALMNAPKMPOLB | |
| SCHEMBL10475124 | 0.75 | POLB (0.50) | GAAKMT2ALMNAPOLBMEN1 | |
| SCHEMBL19568160 | 0.71 | CRHR1 (0.51) | KMT2ALMNAMEN1CRHR1MAPT | |
| SCHEMBL6810703 | 0.71 | GAA (0.41) | GAAKMT2AMEN1CRHR1MAPT | |
| SCHEMBL22790324 | 0.70 | GAA (0.47) | GAAKMT2ALMNAPKMPOLB | |
| SCHEMBL10475343 | 0.69 | GAA (0.62) | GAAKMT2ALMNAPKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4943583-A | PESTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1990-07-24 | — | — | US | disclosed |
| EP-0270061-A2 | Five-membered heterocycles with three heteroatoms, their preparation and their use as pesticides | CIBA-GEIGY AG (CH) | 1988-06-08 | — | — | EP | disclosed |