Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.74 |
| ▸ | GALR3 | O60755 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | PDE3B | Q13370 | 11/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 11/20 | 0.54 |
| ▸ | SLFN12 | Q8IYM2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10474001 | 0.95 | GALR3 (0.76) | MAPTGALR3SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL7273931 | 0.87 | GALR3 (0.79) | MAPTGALR3SMN1; SMN2THRBALDH1A1 | |
| Iodide SCHEMBL10474006 | 0.86 | MAPT (0.71) | MAPTGALR3SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL7273469 | 0.85 | MAPT (0.70) | MAPTGALR3SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL7267555 | 0.85 | GALR3 (0.81) | MAPTGALR3SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL16157214 | 0.85 | MAPT (1.00) | MAPTGALR3SMN1; SMN2THRBALDH1A1 | |
| Iodide SCHEMBL10475201 | 0.84 | GALR3 (0.71) | MAPTGALR3SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL10475491 | 0.84 | MAPT (0.73) | MAPTGALR3SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL7266906 | 0.84 | GALR3 (0.79) | MAPTGALR3SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL16156961 | 0.82 | MAPT (0.79) | MAPTGALR3SMN1; SMN2THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968683-A | INOTROPIC, CARDIOTONIC | HEUMANN PHARMA GMBH & CO. (DE) | 1990-11-06 | — | — | US | disclosed |