Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 11/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12229080 | 0.80 | CYP19A1 (0.56) | CYP19A1ALDH1A1LMNASIGMAR1HRH4 | |
| SCHEMBL18707079 | 0.79 | MEN1 (0.52) | MEN1KMT2A | |
| SCHEMBL16357618 | 0.78 | CYP19A1 (0.54) | MEN1KMT2ACYP19A1ALDH1A1LMNA | |
| SCHEMBL18925110 | 0.77 | CYP19A1 (0.53) | CYP19A1ALDH1A1LMNASIGMAR1HRH4 | |
| SCHEMBL24179955 | 0.77 | SIGMAR1 (0.51) | MEN1KMT2ACYP19A1ALDH1A1LMNA | |
| SCHEMBL23376772 | 0.77 | ALDH1A1 (0.63) | MEN1KMT2ACYP19A1ALDH1A1LMNA | |
| SCHEMBL22887939 | 0.76 | CYP19A1 (0.56) | CYP19A1ALDH1A1LMNASIGMAR1HRH4 | |
| SCHEMBL23376712 | 0.76 | ALDH1A1 (0.62) | MEN1KMT2ACYP19A1ALDH1A1LMNA | |
| SCHEMBL30609094 | 0.76 | MEN1 (0.47) | MEN1KMT2ANPC1 | |
| SCHEMBL28573787 | 0.76 | CYP19A1 (0.51) | CYP19A1ALDH1A1LMNASIGMAR1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990009999-A1 | SECO-NUCLEOSIDE DERIVATIVES AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1990-09-07 | — | — | WO | disclosed |