Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | VCP | P55072 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | PNP | P00491 | 5/20 | 0.57 |
| ▸ | HBB | P68871 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | EDNRA | P25101 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
| ▸ | HPRT1 | P00492 | 7/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13951250 | 0.87 | BLM (0.71) | BLMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL60629 | 0.83 | BLM (0.87) | BLMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3663790 | 0.83 | BLM (0.87) | BLMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL14570090 | 0.83 | BLM (0.75) | BLMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10475485 | 0.83 | BLM (0.75) | BLMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL13523348 | 0.83 | BLM (0.75) | BLMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL29388380 | 0.83 | BLM (0.87) | BLMMEN1KMT2AALDH1A1LMNA | |
| Ganciclovir SCHEMBL3033 | 0.81 | BLM (1.00) | BLMMEN1KMT2AALDH1A1LMNA | |
| Ganciclovir SCHEMBL2160505 | 0.81 | BLM (1.00) | BLMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL13498324 | 0.81 | BLM (0.71) | BLMMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990009998-A1 | NOVEL ACYCLIC NUCLEOSIDE ANALOGUES, PROCESS FOR THEIR PRODUCTION AND USE OF THESE COMPOUNDS AS ANTI-VIRAL DRUGS | BOEHRINGER MANNHEIM GMBH (DE) | 1990-09-07 | — | — | WO | disclosed |