SCHEMBL29388380

SCHEMBL29388380

Nc1nc2c(ncn2COC(CO)C[18F])c(=O)[nH]1

nearest known ligand 0.87

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BLM P54132 2/20 0.87
▸ MEN1 O00255 1/20 0.87
▸ ALDH1A1 P00352 1/20 0.87
▸ LMNA P02545 1/20 0.87
▸ CYP3A4 P08684 1/20 0.87
▸ NFKB1 P19838 1/20 0.87
▸ VCP P55072 1/20 0.87
▸ KMT2A Q03164 1/20 0.87
▸ SMN1; SMN2 Q16637 1/20 0.87
▸ HIF1A Q16665 1/20 0.87
▸ PDE3A Q14432 1/20 0.67
▸ PNP P00491 5/20 0.64
▸ USP2 O75604 1/20 0.64
▸ TSHR P16473 1/20 0.64
▸ EDNRA P25101 1/20 0.64
▸ HTR2A P28223 1/20 0.64
▸ RECQL P46063 1/20 0.64
▸ HBB P68871 1/20 0.64
▸ HSD17B10 Q99714 1/20 0.64
▸ HPRT1 P00492 7/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL60629 1.00 BLM (0.87) BLMMEN1ALDH1A1LMNACYP3A4
SCHEMBL3663790 1.00 BLM (0.87) BLMMEN1ALDH1A1LMNACYP3A4
Ganciclovir SCHEMBL3033 0.93 BLM (1.00) BLMMEN1ALDH1A1LMNACYP3A4
Ganciclovir SCHEMBL2160505 0.93 BLM (1.00) BLMMEN1ALDH1A1LMNACYP3A4
Ganciclovir SCHEMBL10481442 0.92 BLM (0.98) BLMMEN1ALDH1A1LMNACYP3A4
Ganciclovir SCHEMBL2433042 0.92 BLM (0.98) BLMMEN1ALDH1A1LMNACYP3A4
Ganciclovir SCHEMBL25915 0.92 BLM (0.98) BLMMEN1ALDH1A1LMNACYP3A4
Ganciclovir SCHEMBL11121521 0.92 BLM (0.98) BLMMEN1ALDH1A1LMNACYP3A4
Ganciclovir SCHEMBL11093368 0.92 BLM (0.98) BLMMEN1ALDH1A1LMNACYP3A4
Ganciclovir SCHEMBL10899902 0.92 BLM (0.98) BLMMEN1ALDH1A1LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11253611-B2 Thymidine kinase diagnostic assay for gene therapy applications Genvivo, Inc. (US) 2022-02-22 — — US claimed
US-20250345409-A1 COMPOSITIONS AND METHODS FOR THERAPEUTIC OR VACCINE DELIVERY GENVIVO INC (US) 2025-11-13 — — US disclosed
US-12350327-B2 Compositions and methods for therapeutic or vaccine delivery Genvivo, Inc. (US) 2025-07-08 — — US disclosed
US-20250115930-A1 COMPOSITIONS AND METHODS FOR THERAPEUTIC DELIVERY Genvivo, Inc. 2025-04-10 — — US disclosed
US-12234475-B2 Compositions and methods for therapeutic delivery Genvivo, Inc. (US) 2025-02-25 — — US disclosed
US-20240366746-A1 COMPOSITIONS AND METHODS FOR THERAPEUTIC OR VACCINE DELIVERY Genvivo, Inc. 2024-11-07 — — US disclosed
WO-2024226784-A2 COMPOSITIONS AND METHODS FOR THERAPEUTIC OR VACCINE DELIVERY Genvivo, Inc. (US) 2024-10-31 — — WO disclosed
EP-4423288-A2 COMPOSITIONS AND METHODS FOR THERAPEUTIC OR VACCINE DELIVERY GenVivo, Inc. (US) 2024-09-04 — — EP disclosed
EP-4423287-A2 COMPOSITIONS AND METHODS FOR THERAPEUTIC DELIVERY GenVivo, Inc. (US) 2024-09-04 — — EP disclosed
CN-118556129-A Compositions and methods for therapeutic agent delivery 吉恩维沃公司 2024-08-27 — — CN disclosed
WO-2023076177-A2 COMPOSITIONS AND METHODS FOR THERAPEUTIC DELIVERY Genvivo, Inc. (US) 2023-05-04 — — WO disclosed
WO-2023076180-A2 COMPOSITIONS AND METHODS FOR THERAPEUTIC OR VACCINE DELIVERY Genvivo, Inc. (US) 2023-05-04 — — WO disclosed
EP-4126867-A1 THIOPURINE-BASED COMPOUND, COMPOSITION, METHOD OF PREPARATION AND APPLICATIONS SeeCure Taiwan Co., Ltd. (TW) 2023-02-08 — — EP disclosed
US-20220401581-A1 THYMIDINE KINASE GENE Genvivo, Inc. 2022-12-22 — — US disclosed
CN-115298178-A Thiopurine compound, composition, preparation method and application 聚天生医股份有限公司 2022-11-04 — — CN disclosed
WO-2022178840-A1 THIOPURINE-BASED COMPOUND, COMPOSITION, METHOD OF PREPARATION AND APPLICATIONS SEECURE TAIWAN CO. , LTD. (CN) 2022-09-01 — — WO disclosed
US-11364307-B2 Thymidine kinase gene Genvivo, Inc. (US) 2022-06-21 — — US disclosed
WO-2022099209-A1 BIO-FUNCTIONALIZATION OF WATER-SOLUBLE POLY(PHENYLENE ETHYNYLENE)S BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2022-05-12 — — WO disclosed
US-11253611-B2 Thymidine kinase diagnostic assay for gene therapy applications Genvivo, Inc. (US) 2022-02-22 — — US disclosed
US-11242314-B2 Synthesizing pet tracers using [F-18]sulfonyl fluoride as a source of [F-18]fluoride WASHINGTON UNIVERSITY (US) 2022-02-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11242314-B2 Synthesizing pet tracers using [F-18]sulfonyl fluoride as a source of [F-18]fluoride STX18, GPR119, SLC5A1 BLM 3654/4885MEN1 250/4885ALDH1A1 2643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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