Benzene

Benzene

SCHEMBL10475772

C#C.CCCC.CCCCO.c1ccccc1

nearest known ligand 0.65

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.65
SMN1; SMN2 Q16637 1/20 0.53
LMNA P02545 3/20 0.50
TSHR P16473 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
HSD17B10 Q99714 1/20 0.50
PCSK9 Q8NBP7 1/20 0.33
PTGS2 P35354 1/20 0.32
ABCB11 O95342 1/20 0.32
ESR1 P03372 1/20 0.32
PGR P06401 1/20 0.32
CHRM2 P08172 1/20 0.32
HTR1A P08908 1/20 0.32
ADRA2A P08913 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
CHRM1 P11229 1/20 0.32
DRD1 P21728 1/20 0.32
TBXA2R P21731 1/20 0.32
ACHE P22303 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL515817 0.91 ALDH1A1 (0.79) ALDH1A1SMN1; SMN2LMNATSHRMEN1
Benzene SCHEMBL28051358 0.88 ALDH1A1 (0.73) ALDH1A1SMN1; SMN2LMNATSHRMEN1
Benzene SCHEMBL9183281 0.88 ALDH1A1 (0.73) ALDH1A1SMN1; SMN2LMNATSHRMEN1
Benzene SCHEMBL11653237 0.88 ALDH1A1 (0.73) ALDH1A1SMN1; SMN2LMNATSHRMEN1
Butyl Alcohol SCHEMBL28329569 0.87
Benzene SCHEMBL7901180 0.85 ALDH1A1 (0.69) ALDH1A1SMN1; SMN2LMNATSHRMEN1
Butyl Alcohol SCHEMBL11880049 0.84
Butyl Alcohol SCHEMBL10442227 0.84
1-Hexanol SCHEMBL825298 0.82 ALDH1A1 (0.77) ALDH1A1SMN1; SMN2LMNATSHRMEN1
1-Pentanol SCHEMBL29189685 0.81 SMN1; SMN2 (0.80) ALDH1A1SMN1; SMN2LMNATSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8225908-B1 Elevator escape system including elevator cab detachable from an interposing device SCHMUTTER BRUCE E (US) 2012-07-24 US disclosed