Benzene

Benzene

SCHEMBL9183281

CCCCO.CO.c1ccccc1

nearest known ligand 0.73

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.73
SMN1; SMN2 Q16637 1/20 0.59
TSHR P16473 4/20 0.56
LMNA P02545 3/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
HSD17B10 Q99714 1/20 0.56
PCSK9 Q8NBP7 1/20 0.36
THRB P10828 2/20 0.35
AKR1B1 P15121 1/20 0.35
ABCB11 O95342 1/20 0.35
ESR1 P03372 1/20 0.35
PGR P06401 1/20 0.35
CHRM2 P08172 1/20 0.35
HTR1A P08908 1/20 0.35
ADRA2A P08913 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
CHRM1 P11229 1/20 0.35
DRD1 P21728 1/20 0.35
TBXA2R P21731 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL7901180 0.97 ALDH1A1 (0.69) ALDH1A1SMN1; SMN2TSHRLMNAMEN1
Benzene SCHEMBL515817 0.97 ALDH1A1 (0.79) ALDH1A1SMN1; SMN2TSHRLMNAMEN1
Benzene SCHEMBL28051358 0.93 ALDH1A1 (0.73) ALDH1A1SMN1; SMN2TSHRLMNAMEN1
Benzene SCHEMBL11653237 0.93 ALDH1A1 (0.73) ALDH1A1SMN1; SMN2TSHRLMNAMEN1
Butyl Alcohol SCHEMBL28251078 0.89
Butyl Alcohol SCHEMBL502753 0.89
Butyl Alcohol SCHEMBL48476 0.89
Butyl Alcohol SCHEMBL11880049 0.89
1-Hexanol SCHEMBL825298 0.88 ALDH1A1 (0.77) ALDH1A1SMN1; SMN2TSHRLMNAMEN1
Benzene SCHEMBL10475772 0.88 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2TSHRLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0375439-B1 Geminal diphenyl derivatives and their use in immunoassays SYNTEX INC (US) 1995-09-06 EP disclosed
US-5378636-A M-phenoxybenzoylaminoethanesulfonic acid to inactivate interfering binding proteins in immunoassay SYNTEX (U.S.A.) INC. (US) 1995-01-03 US disclosed
US-5256575-A For inactivating interfering binding proteins SYNTEX (U.S.A.) INC. (US) 1993-10-26 US disclosed
EP-0375439-A2 Geminal diphenyl derivatives and their use in immunoassays SYNTEX (U.S.A.) INC. (US) 1990-06-27 EP disclosed